| Originalsprog | Engelsk |
|---|---|
| Titel | Encyclopedia of Life Support Systems (EOLSS) : MATHEMATICAL PHYSIOLOGY |
| Redaktører | Andrea De Gaetano |
| Antal sider | 10 |
| Forlag | Eolss Publishers, Oxford, UK, [http://www.eolss.net] |
| Publikationsdato | 2010 |
| Status | Udgivet - 2010 |
Abstract
This chapter provides an overview of mathematical models of the hemo- and
hydrodynamics of the kidneys. These models have been developed over the last two
decades, mainly motivated by experimental evidence of spontaneous tubular pressure
oscillations in the nephron tubule, the functional unit of the kidney, thus extending the
existing models of a steady state nature. More recent observations reveal that the
oscillations in single nephrons are synchronized with neighboring nephrons, and to get a
complete picture of the physiological mechanisms, models incorporating the interactions
between ensembles of nephrons should be considered. Here merely single nephron
models are considered, which are the building blocks of more complex models, only
giving models of coupled nephrons a short treatment in the end.
hydrodynamics of the kidneys. These models have been developed over the last two
decades, mainly motivated by experimental evidence of spontaneous tubular pressure
oscillations in the nephron tubule, the functional unit of the kidney, thus extending the
existing models of a steady state nature. More recent observations reveal that the
oscillations in single nephrons are synchronized with neighboring nephrons, and to get a
complete picture of the physiological mechanisms, models incorporating the interactions
between ensembles of nephrons should be considered. Here merely single nephron
models are considered, which are the building blocks of more complex models, only
giving models of coupled nephrons a short treatment in the end.
| Navn | Mathematical Physiology |
|---|