Matrix metalloproteinase-8 overexpression prevents proper tissue repair

Patricia L Danielsen; Anders V Holst; Henrik R Maltesen; Maria R Bassi; Peter J Holst; Katja M Heinemeier; Jørgen Olsen; Carl Christian Danielsen; Steen S Poulsen; Lars N Jorgensen; Magnus S Agren

doi:10.1016/j.surg.2011.06.016

Matrix metalloproteinase-8 overexpression prevents proper tissue repair

Patricia L Danielsen, Anders V Holst, Henrik R Maltesen, Maria R Bassi, Peter J Holst, Katja M Heinemeier, Jørgen Olsen, Carl Christian Danielsen, Steen S Poulsen, Lars N Jorgensen, Magnus S Agren

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

43 Citationer (Scopus)

Abstract

The collagenolytic matrix metalloproteinase-8 (MMP-8) is essential for normal tissue repair but is often overexpressed in wounds with disrupted healing. Our aim was to study the impact of a local excess of this neutrophil-derived proteinase on wound healing using recombinant adenovirus-driven transduction of full-length Mmp8 (AdMMP-8).

Originalsprog	Engelsk
Tidsskrift	Surgery
Vol/bind	150
Udgave nummer	5
Sider (fra-til)	897-906
Antal sider	10
ISSN	0263-9319
DOI	https://doi.org/10.1016/j.surg.2011.06.016
Status	Udgivet - 2011

Adgang til dokumentet

10.1016/j.surg.2011.06.016

Citationsformater

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title = "Matrix metalloproteinase-8 overexpression prevents proper tissue repair",

abstract = "The collagenolytic matrix metalloproteinase-8 (MMP-8) is essential for normal tissue repair but is often overexpressed in wounds with disrupted healing. Our aim was to study the impact of a local excess of this neutrophil-derived proteinase on wound healing using recombinant adenovirus-driven transduction of full-length Mmp8 (AdMMP-8).",

author = "Danielsen, {Patricia L} and Holst, {Anders V} and Maltesen, {Henrik R} and Bassi, {Maria R} and Holst, {Peter J} and Heinemeier, {Katja M} and J{\o}rgen Olsen and Danielsen, {Carl Christian} and Poulsen, {Steen S} and Jorgensen, {Lars N} and Agren, {Magnus S}",

year = "2011",

doi = "10.1016/j.surg.2011.06.016",

language = "English",

volume = "150",

pages = "897--906",

journal = "Surgery",

issn = "0263-9319",

publisher = "TheMedicine Publishing Company",

number = "5",

}

TY - JOUR

T1 - Matrix metalloproteinase-8 overexpression prevents proper tissue repair

AU - Danielsen, Patricia L

AU - Holst, Anders V

AU - Maltesen, Henrik R

AU - Bassi, Maria R

AU - Holst, Peter J

AU - Heinemeier, Katja M

AU - Olsen, Jørgen

AU - Danielsen, Carl Christian

AU - Poulsen, Steen S

AU - Jorgensen, Lars N

AU - Agren, Magnus S

PY - 2011

Y1 - 2011

N2 - The collagenolytic matrix metalloproteinase-8 (MMP-8) is essential for normal tissue repair but is often overexpressed in wounds with disrupted healing. Our aim was to study the impact of a local excess of this neutrophil-derived proteinase on wound healing using recombinant adenovirus-driven transduction of full-length Mmp8 (AdMMP-8).

AB - The collagenolytic matrix metalloproteinase-8 (MMP-8) is essential for normal tissue repair but is often overexpressed in wounds with disrupted healing. Our aim was to study the impact of a local excess of this neutrophil-derived proteinase on wound healing using recombinant adenovirus-driven transduction of full-length Mmp8 (AdMMP-8).

U2 - 10.1016/j.surg.2011.06.016

DO - 10.1016/j.surg.2011.06.016

M3 - Journal article

C2 - 21875735

SN - 0263-9319

VL - 150

SP - 897

EP - 906

JO - Surgery

JF - Surgery

IS - 5

ER -