@article{877c8be05d82410d968c89c88aa26ed4,
title = "Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration",
abstract = "The glucose-lowering drug metformin has been shown to inhibit complex I of the mitochondrial electron transport chain in skeletal muscle. To investigate this effect in vivo we studied skeletal muscle mitochondrial respiratory capacity and content from patients with type 2 diabetes treated with metformin (n = 14) or sulfonylurea (n = 8) and healthy control (n = 18) participants.",
keywords = "Blood Glucose, Body Mass Index, Case-Control Studies, Cell Respiration, Citrate (si)-Synthase, Diabetes Mellitus, Type 2, Electron Transport Complex I, Hemoglobin A, Glycosylated, Humans, Hypoglycemic Agents, Insulin, Male, Metformin, Middle Aged, Models, Biological, Muscle, Skeletal, Oxygen Consumption, Sulfonylurea Compounds",
author = "Steen Larsen and R Rab{\o}l and Hansen, {C N} and S Madsbad and Helge, {J W} and F Dela",
year = "2012",
doi = "10.1007/s00125-011-2340-0",
language = "English",
volume = "55",
pages = "443--9",
journal = "Diabetologia",
issn = "0012-186X",
publisher = "Springer",
number = "2",
}