Molekylaer patogenese ved monogen og polygen fedme

Philip J Larsen, Søren Morgenthaler Echwald, Thorkild I A Sørensen, Oluf Borbye Pedersen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

1 Citationer (Scopus)

Abstract

During the last few years, studies of the molecular pathogenesis of obesity both in mouse models and in the rare cases of monogenic obesity in humans have added significantly to our understanding of the key role of the hypothalamus in mediating hunger and satiety. These insights have brought us closer to the development of rational therapies of obesity, the epidemic of which is continuing in the post-industrial society, which is characterised by sedentary behaviour patterns.
Bidragets oversatte titelMolecular pathogenesis in monogenic and polygenic obesity
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind168
Udgave nummer2
Sider (fra-til)152-5
Antal sider4
ISSN0041-5782
StatusUdgivet - 2006

Emneord

  • Animals
  • Appetite
  • Humans
  • Hypothalamus
  • Mice
  • Obesity
  • Receptors, Cell Surface
  • Receptors, Leptin
  • Satiation

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