Mortality and causes of death in autism spectrum disorders: An update.

Svend Erik Mouridsen; Henrik Brønnum-Hansen; Bente Rich; Torben Isager

doi:10.1177/1362361308091653

Mortality and causes of death in autism spectrum disorders: An update.

Svend Erik Mouridsen, Henrik Brønnum-Hansen, Bente Rich, Torben Isager

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

123 Citationer (Scopus)

Abstract

Udgivelsesdato: 2008-Jul

Originalsprog	Engelsk
Tidsskrift	Autism
Vol/bind	12
Udgave nummer	4
Sider (fra-til)	403-14
Antal sider	11
ISSN	1362-3613
DOI	https://doi.org/10.1177/1362361308091653
Status	Udgivet - 1 jul. 2008
Udgivet eksternt	Ja

Adgang til dokumentet

10.1177/1362361308091653

Citationsformater

@article{204be51eb98342a7a0b1ae4554661684,

title = "Mortality and causes of death in autism spectrum disorders: An update.",

abstract = "This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960-93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths.",

author = "Mouridsen, {Svend Erik} and Henrik Br{\o}nnum-Hansen and Bente Rich and Torben Isager",

year = "2008",

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doi = "10.1177/1362361308091653",

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TY - JOUR

T1 - Mortality and causes of death in autism spectrum disorders: An update.

AU - Mouridsen, Svend Erik

AU - Brønnum-Hansen, Henrik

AU - Rich, Bente

AU - Isager, Torben

PY - 2008/7/1

Y1 - 2008/7/1

N2 - This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960-93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths.

AB - This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960-93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths.

U2 - 10.1177/1362361308091653

DO - 10.1177/1362361308091653

M3 - Journal article

C2 - 18579647

VL - 12

SP - 403

EP - 414

JO - Autism

JF - Autism

SN - 1362-3613

IS - 4

ER -