Mortality and causes of death in autism spectrum disorders - An update

S.E. Mouridsen; H.B. Hansen; B. Rich; T. Isager

Mortality and causes of death in autism spectrum disorders - An update

S.E. Mouridsen, H.B. Hansen, B. Rich, T. Isager

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

135 Citationer (Scopus)

Abstract

This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960-93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths
Udgivelsesdato: 2008/7

Originalsprog	Engelsk
Tidsskrift	Autism
Vol/bind	12
Udgave nummer	4
Sider (fra-til)	403-414
Antal sider	11
ISSN	1362-3613
Status	Udgivet - 2008

Bibliografisk note

Times Cited: 0ArticleEnglishMouridsen, S. EBispebjerg Hosp, Copenhagen, DenmarkCited References Count: 24331ASSAGE PUBLICATIONS LTD1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLANDLONDON

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Citationsformater

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abstract = "This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960-93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths Udgivelsesdato: 2008/7",

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T1 - Mortality and causes of death in autism spectrum disorders - An update

AU - Mouridsen, S.E.

AU - Hansen, H.B.

AU - Rich, B.

AU - Isager, T.

N1 - Times Cited: 0ArticleEnglishMouridsen, S. EBispebjerg Hosp, Copenhagen, DenmarkCited References Count: 24331ASSAGE PUBLICATIONS LTD1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLANDLONDON

PY - 2008

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N2 - This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960-93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths Udgivelsesdato: 2008/7

AB - This study compared mortality among Danish citizens with autism spectrum disorders (ASDs) with that of the general population. A clinical cohort of 341 Danish individuals with variants of ASD, previously followed over the period 1960-93, now on average 43 years of age, were updated with respect to mortality and causes of death. Standardized mortality ratios (SMRs) were calculated for various times after diagnosis. In all, 26 persons with ASD had died, whereas the expected number of deaths was 13.5. Thus the mortality risk among those with ASD was nearly twice that of the general population. The SMR was particularly high in females. The excess mortality risk has remained unchanged since our first study in 1993. Eight of the 26 deaths were associated with epilepsy and four died from epilepsy. Future staff education should focus on better managing of the complex relationships between ASD and physical illness to prevent avoidable deaths Udgivelsesdato: 2008/7

M3 - Journal article

SN - 1362-3613

VL - 12

SP - 403

EP - 414

JO - Autism

JF - Autism

IS - 4

ER -