Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

Katharina H. Clitherow; Craig Murdoch; Sebastian Guy Spain; Anna Mette Handler; Helen E. Colley; Mai Bay Stie; Hanne Morck Nielsen; Christian Janfelt; Paul V. Hatton; Jette Jacobsen

doi:10.1021/acs.molpharmaceut.9b00535

Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging

Katharina H. Clitherow, Craig Murdoch, Sebastian Guy Spain, Anna Mette Handler, Helen E. Colley, Mai Bay Stie, Hanne Morck Nielsen, Christian Janfelt, Paul V. Hatton, Jette Jacobsen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

33 Citationer (Scopus)

214 Downloads (Pure)

Originalsprog	Engelsk
Tidsskrift	Molecular Pharmaceutics
Vol/bind	16
Udgave nummer	9
Sider (fra-til)	3948-3956
ISSN	1543-8384
DOI	https://doi.org/10.1021/acs.molpharmaceut.9b00535
Status	Udgivet - sep. 2019

Adgang til dokumentet

10.1021/acs.molpharmaceut.9b00535Licens: CC BY

acs.molpharmaceut.9b00535Forlagets udgivne version, 5,74 MBLicens: CC BY

Citationsformater

Clitherow, K. H., Murdoch, C., Spain, S. G., Handler, A. M., Colley, H. E., Stie, M. B., Nielsen, H. M., Janfelt, C., Hatton, P. V., & Jacobsen, J. (2019). Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging. Molecular Pharmaceutics, 16(9), 3948-3956. https://doi.org/10.1021/acs.molpharmaceut.9b00535

Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging. / Clitherow, Katharina H.; Murdoch, Craig; Spain, Sebastian Guy et al.
I: Molecular Pharmaceutics, Bind 16, Nr. 9, 09.2019, s. 3948-3956.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Clitherow, KH, Murdoch, C, Spain, SG, Handler, AM, Colley, HE, Stie, MB , Nielsen, HM , Janfelt, C, Hatton, PV & Jacobsen, J 2019, 'Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging', Molecular Pharmaceutics, bind 16, nr. 9, s. 3948-3956. https://doi.org/10.1021/acs.molpharmaceut.9b00535

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title = "Mucoadhesive Electrospun Patch Delivery of Lidocaine to the Oral Mucosa and Investigation of Spatial Distribution in a Tissue Using MALDI-Mass Spectrometry Imaging",

keywords = "electrospinning, lidocaine, oral mucosa, ex vivo tissue permeation, MALDI-mass spectrometry imaging, drug distribution in tissue",

author = "Clitherow, {Katharina H.} and Craig Murdoch and Spain, {Sebastian Guy} and Handler, {Anna Mette} and Colley, {Helen E.} and Stie, {Mai Bay} and Nielsen, {Hanne Morck} and Christian Janfelt and Hatton, {Paul V.} and Jette Jacobsen",

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AU - Clitherow, Katharina H.

AU - Murdoch, Craig

AU - Spain, Sebastian Guy

AU - Handler, Anna Mette

AU - Colley, Helen E.

AU - Stie, Mai Bay

AU - Nielsen, Hanne Morck

AU - Janfelt, Christian

AU - Hatton, Paul V.

AU - Jacobsen, Jette

PY - 2019/9

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KW - electrospinning

KW - lidocaine

KW - oral mucosa

KW - ex vivo tissue permeation

KW - MALDI-mass spectrometry imaging

KW - drug distribution in tissue

U2 - 10.1021/acs.molpharmaceut.9b00535

DO - 10.1021/acs.molpharmaceut.9b00535

M3 - Journal article

C2 - 31361498

SN - 1543-8384

VL - 16

SP - 3948

EP - 3956

JO - Molecular Pharmaceutics

JF - Molecular Pharmaceutics

IS - 9

ER -