n-3 PUFA status in school children is associated with beneficial lipid profile, reduced physical activity and increased blood pressure in boys

Camilla Trab Damsgaard, Ken D Stark, Mads Fiil Hjorth, Anja Biltoft-Jensen, Arne Astrup, Kim F Michaelsen, Lotte Lauritzen

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

40 Citationer (Scopus)

Abstract

Dietary n-3 long-chain PUFA (LC-PUFA) improve dyslipidaemia and hypertension and may affect insulin resistance and adiposity. Increasing numbers of children show signs of the metabolic syndrome (MetS), but few studies have investigated the association with n-3 LC-PUFA status. We examined the relationship between fasting whole-blood EPA or DHA (w/w% of the total fatty acids, FA%) and markers of the MetS (anthropometry, blood pressure, plasma lipids and glucose homeostasis) cross-sectionally in seventy-three 8-11-year-old Danish children from the OPUS School Meal Pilot Study (OPUS is an acronym of the project 'Optimal well-being, development and health for Danish children through a healthy New Nordic Diet' and is supported by a grant from the Nordea Foundation). Also, we explored the potential mediating effects of physical activity and energy intake. Girls had higher body fat percentage (BF%), diastolic blood pressure, heart rate, plasma TAG, insulin, homeostasis model assessment-insulin resistance and glycosylated Hb than boys. Sexes did not differ in fish or macronutrient intake or whole-blood fatty acids. After adjustment for sex, age and total whole-blood fatty acid concentration, BF% and HDL:TAG increased with whole-blood EPA (ß>0·25, P
OriginalsprogEngelsk
TidsskriftBritish Journal of Nutrition
Vol/bind110
Udgave nummer7
Sider (fra-til)1304-1312
Antal sider9
ISSN0007-1145
DOI
StatusUdgivet - 2013

Bibliografisk note

CURIS 2013 NEXS 079

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