Abstract
Infection in mice (BALB/cABom) with the intestinal trematode Echinostoma caproni had a negative influence on pregnancy. The effect of the infection set in immediately following implantation (day 5 of pregnancy) resulting in fewer foetuses being present in infected mice on day 9 than in the controls. Ovulation, fertilization of eggs, and implantation itself were obviously not impaired. The infected mice had significantly lower serum progesterone levels on day 5 of pregnancy than the non-infected controls. It is speculated that the progesterone levels in the infected female mice were too low to secure early post-implantation gestation.
Originalsprog | Engelsk |
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Tidsskrift | Parasitology |
Vol/bind | 102 |
Udgave nummer | 3 |
Sider (fra-til) | 387-390 |
Antal sider | 4 |
ISSN | 0031-1820 |
DOI | |
Status | Udgivet - jun. 1991 |
Bibliografisk note
Funding Information:We wish to thank Mrs Lisbet Kiorboe for expert technical assistance, and Mrs Alice Scheuer and Mr Kenneth Worm for assistance with animal handling and blood sampling. We thank the staff at the Danish Bilharziasis Laboratory for infecting the mice with Echinostoma caproni, and we thank Dr Ebba Nexo, the Central Hospital, Hillerod, for having performed the measurements of oestrogens and progesterone. Financial support was received from the Danish Agricultural and Veterinary Research Council, grant 13-4185.