Neural mechanisms of voluntary and involuntary recall: a PET study

Nicoline Marie Hall; Albert Gjedde; Ron Kupers

doi:10.1016/j.bbr.2007.08.026

Neural mechanisms of voluntary and involuntary recall: a PET study

Nicoline Marie Hall, Albert Gjedde, Ron Kupers

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

72 Citationer (Scopus)

Abstract

Udgivelsesdato: 2008-Jan-25

Originalsprog	Engelsk
Tidsskrift	Behavioural Brain Research
Vol/bind	186
Udgave nummer	2
Sider (fra-til)	261-72
Antal sider	11
ISSN	0166-4328
DOI	https://doi.org/10.1016/j.bbr.2007.08.026
Status	Udgivet - 2007
Udgivet eksternt	Ja

Bibliografisk note

Keywords: Adult; Brain Mapping; Cerebral Cortex; Cerebrovascular Circulation; Female; Humans; Male; Mental Recall; Neuropsychological Tests; Positron-Emission Tomography

Adgang til dokumentet

10.1016/j.bbr.2007.08.026

Citationsformater

@article{dc7717508a6011df928f000ea68e967b,

title = "Neural mechanisms of voluntary and involuntary recall: a PET study",

abstract = "Neuropsychological and neuroimaging studies on episodic memory retrieval have primarily focused on volitional memory tasks. However, some conscious memories arise involuntarily, i.e. without a strategic retrieval attempt, yet little is known about the neural network underlying involuntary episodic memory. The aim of this study was to determine whether voluntary and involuntary recall are mediated by separate cortical networks. We used positron emission tomography (PET) to measure changes in regional cerebral blood flow (rCBF) in 12 healthy subjects during voluntary and involuntary cued recall of pictures and a control condition with no episodic memory requirements. Involuntary recall was elicited by using an incidental memory task. Compared to the control condition, voluntary and involuntary recall were both associated with significant regional cerebral blood flow (rCBF) increases in posterior cingulate gyrus (PCG; BA 23), left precuneus (BA 7), and right parahippocampal gyrus (BA 35/36). In addition, rCBF in right dorsolateral prefrontal cortex (PFC; BA 8/9) and left precuneus (BA 7) was significantly larger during voluntary compared to involuntary recall, while rCBF was enhanced in left dorsolateral PFC (BA 9) during involuntary recall. The findings corroborate an association of the right PFC with a strategic component of episodic memory retrieval. Moreover, they show for the first time that it is possible to activate the medial temporal lobe, the PCG, and the precuneus, regions normally associated with retrieval success, without this strategic element. The relatively higher activity in precuneus during voluntary compared to involuntary recall suggests that activity in this region co-varies not only with retrieval success but also with retrieval intentionality.",

author = "Hall, {Nicoline Marie} and Albert Gjedde and Ron Kupers",

note = "Keywords: Adult; Brain Mapping; Cerebral Cortex; Cerebrovascular Circulation; Female; Humans; Male; Mental Recall; Neuropsychological Tests; Positron-Emission Tomography",

year = "2007",

doi = "10.1016/j.bbr.2007.08.026",

language = "English",

volume = "186",

pages = "261--72",

journal = "Behavioural Brain Research",

issn = "0166-4328",

publisher = "Elsevier",

number = "2",

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TY - JOUR

T1 - Neural mechanisms of voluntary and involuntary recall: a PET study

AU - Hall, Nicoline Marie

AU - Gjedde, Albert

AU - Kupers, Ron

N1 - Keywords: Adult; Brain Mapping; Cerebral Cortex; Cerebrovascular Circulation; Female; Humans; Male; Mental Recall; Neuropsychological Tests; Positron-Emission Tomography

PY - 2007

Y1 - 2007

N2 - Neuropsychological and neuroimaging studies on episodic memory retrieval have primarily focused on volitional memory tasks. However, some conscious memories arise involuntarily, i.e. without a strategic retrieval attempt, yet little is known about the neural network underlying involuntary episodic memory. The aim of this study was to determine whether voluntary and involuntary recall are mediated by separate cortical networks. We used positron emission tomography (PET) to measure changes in regional cerebral blood flow (rCBF) in 12 healthy subjects during voluntary and involuntary cued recall of pictures and a control condition with no episodic memory requirements. Involuntary recall was elicited by using an incidental memory task. Compared to the control condition, voluntary and involuntary recall were both associated with significant regional cerebral blood flow (rCBF) increases in posterior cingulate gyrus (PCG; BA 23), left precuneus (BA 7), and right parahippocampal gyrus (BA 35/36). In addition, rCBF in right dorsolateral prefrontal cortex (PFC; BA 8/9) and left precuneus (BA 7) was significantly larger during voluntary compared to involuntary recall, while rCBF was enhanced in left dorsolateral PFC (BA 9) during involuntary recall. The findings corroborate an association of the right PFC with a strategic component of episodic memory retrieval. Moreover, they show for the first time that it is possible to activate the medial temporal lobe, the PCG, and the precuneus, regions normally associated with retrieval success, without this strategic element. The relatively higher activity in precuneus during voluntary compared to involuntary recall suggests that activity in this region co-varies not only with retrieval success but also with retrieval intentionality.

AB - Neuropsychological and neuroimaging studies on episodic memory retrieval have primarily focused on volitional memory tasks. However, some conscious memories arise involuntarily, i.e. without a strategic retrieval attempt, yet little is known about the neural network underlying involuntary episodic memory. The aim of this study was to determine whether voluntary and involuntary recall are mediated by separate cortical networks. We used positron emission tomography (PET) to measure changes in regional cerebral blood flow (rCBF) in 12 healthy subjects during voluntary and involuntary cued recall of pictures and a control condition with no episodic memory requirements. Involuntary recall was elicited by using an incidental memory task. Compared to the control condition, voluntary and involuntary recall were both associated with significant regional cerebral blood flow (rCBF) increases in posterior cingulate gyrus (PCG; BA 23), left precuneus (BA 7), and right parahippocampal gyrus (BA 35/36). In addition, rCBF in right dorsolateral prefrontal cortex (PFC; BA 8/9) and left precuneus (BA 7) was significantly larger during voluntary compared to involuntary recall, while rCBF was enhanced in left dorsolateral PFC (BA 9) during involuntary recall. The findings corroborate an association of the right PFC with a strategic component of episodic memory retrieval. Moreover, they show for the first time that it is possible to activate the medial temporal lobe, the PCG, and the precuneus, regions normally associated with retrieval success, without this strategic element. The relatively higher activity in precuneus during voluntary compared to involuntary recall suggests that activity in this region co-varies not only with retrieval success but also with retrieval intentionality.

U2 - 10.1016/j.bbr.2007.08.026

DO - 10.1016/j.bbr.2007.08.026

M3 - Journal article

C2 - 17913256

SN - 0166-4328

VL - 186

SP - 261

EP - 272

JO - Behavioural Brain Research

JF - Behavioural Brain Research

IS - 2

ER -