NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)

Sofie L. Broholm, Simone Gramsbergen, Nils Nyberg, Anna Jäger, Dan Stærk

Publikation: KonferencebidragPosterForskning

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Abstract

Type 2 diabetes is a metabolic disorder estimated to affect millions of people all over the world.1 One way of reducing diabetes-related complications is to control
postprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood glucose levels. A study from 2011
shows that berries from Sorbus spp (rowan berries) effectively inhibit α-amylase activity and suggests that the active compounds are proanthocyanidins.3 The aim of this
project is to identify the rowan berry species with highest α-amylase inhibitory activity - and to find a 1H-NMR method suitable for NMR-based metabolomics
OriginalsprogEngelsk
Publikationsdato2015
Antal sider1
StatusUdgivet - 2015
Begivenhed36th Danish NMR Meeting - Lund, Sverige
Varighed: 19 jan. 201520 jan. 2015

Konference

Konference36th Danish NMR Meeting
Land/OmrådeSverige
ByLund
Periode19/01/201520/01/2015

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