NUT carcinoma presenting in the palate: a case report

Libana Raffoul Bjornstrup, Jesper Reibel, Katalin Kiss, Morten Schioedt

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4 Citationer (Scopus)

Abstract

NUT carcinomas (NC) are rare and aggressive tumours characterized by chromosomal rearrangements of the gene encoding for nuclear protein of the testis (NUT) located on chromosome 15q14. This article presents a case of a 60-year-old woman diagnosed with NC presenting as a fast growing primary tumour in the right palate. Further evaluation revealed a tumour mass in the lungs and widespread metastases. A review of the literature did not reveal earlier cases presenting in the palate. In order to improve early diagnosis it is suggested to perform immunohistochemical testing for NUT in all poorly differentiated carcinomas without glandular differentiation arising in the chest, and head and neck (Clin Cancer Res, 18, 2012, 5773).

OriginalsprogEngelsk
TidsskriftAPMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Vol/bind125
Udgave nummer10
Sider (fra-til)933-936
Antal sider4
ISSN0903-4641
DOI
StatusUdgivet - okt. 2017

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