Nutrients men-TOR β-Cells to Adulthood

Keiichi Katsumoto; Anne Grapin-Botton

doi:10.1016/j.devcel.2020.06.028

Nutrients men-TOR β-Cells to Adulthood

Keiichi Katsumoto, Anne Grapin-Botton

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

2 Citationer (Scopus)

Abstract

A major trigger of adult β-cell insulin secretion is glucose. In a recent issue of Cell Metabolism, Helman and colleagues show that in fetuses insulin secretion depends on the activation of mTOR by amino acids and that reducing amino acids promotes maturation of β-cells derived from pluripotent stem cells.

Originalsprog	Engelsk
Tidsskrift	Developmental Cell
Vol/bind	54
Udgave nummer	2
Sider (fra-til)	140-141
Antal sider	2
ISSN	1534-5807
DOI	https://doi.org/10.1016/j.devcel.2020.06.028
Status	Udgivet - 20 jul. 2020

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Citationsformater

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title = "Nutrients men-TOR β-Cells to Adulthood",

abstract = "A major trigger of adult β-cell insulin secretion is glucose. In a recent issue of Cell Metabolism, Helman and colleagues show that in fetuses insulin secretion depends on the activation of mTOR by amino acids and that reducing amino acids promotes maturation of β-cells derived from pluripotent stem cells.",

keywords = "Adult, Glucose/metabolism, Humans, Infant, Newborn, Insulin/metabolism, Insulin Secretion, Insulin-Secreting Cells/metabolism, Male, Nutrients",

author = "Keiichi Katsumoto and Anne Grapin-Botton",

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AU - Katsumoto, Keiichi

AU - Grapin-Botton, Anne

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KW - Adult

KW - Glucose/metabolism

KW - Humans

KW - Infant, Newborn

KW - Insulin/metabolism

KW - Insulin Secretion

KW - Insulin-Secreting Cells/metabolism

KW - Male

KW - Nutrients

U2 - 10.1016/j.devcel.2020.06.028

DO - 10.1016/j.devcel.2020.06.028

M3 - Journal article

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SN - 1534-5807

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JO - Developmental Cell

JF - Developmental Cell

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