On-chip electromembrane extraction for monitoring drug metabolism in real time by electrospray ionization mass spectrometry

Nickolaj J. Petersen; Henrik Jensen; Stig Pedersen-Bjergaard

doi:10.1007/978-1-4939-2353-3_15

On-chip electromembrane extraction for monitoring drug metabolism in real time by electrospray ionization mass spectrometry

Nickolaj J. Petersen, Henrik Jensen, Stig Pedersen-Bjergaard

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

8 Citationer (Scopus)

Abstract

Sample preparation is an essential step in any bioanalytical procedure and very often the most challenging step in method development. Most of the currently used methods require a relatively large amount of sample and are time consuming. Here, we describe a new approach based on electromembrane extraction (EME) integrated in microfluidic polymer chips. This procedure is fast, requires only small amounts of sample, and may thus be used for monitoring drug metabolism and the formation of metabolites in real time.

Originalsprog	Engelsk
Titel	Microchip Capillary Electrophoresis Protocols
Redaktører	Ann Van Schepdael
Antal sider	12
Vol/bind	1274
Forlag	Humana Press
Publikationsdato	2015
Sider	171-82
Kapitel	15
ISBN (Trykt)	978-1-4939-2352-6
ISBN (Elektronisk)	978-1-4939-2353-3
DOI	https://doi.org/10.1007/978-1-4939-2353-3_15
Status	Udgivet - 2015

Navn	Methods in molecular biology (Clifton, N.J.)

Adgang til dokumentet

10.1007/978-1-4939-2353-3_15

Citationsformater

On-chip electromembrane extraction for monitoring drug metabolism in real time by electrospray ionization mass spectrometry. / Petersen, Nickolaj J.; Jensen, Henrik; Pedersen-Bjergaard, Stig.
Microchip Capillary Electrophoresis Protocols. red. / Ann Van Schepdael. Bind 1274 Humana Press, 2015. s. 171-82 (Methods in molecular biology (Clifton, N.J.)).

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › peer review

Petersen, NJ, Jensen, H & Pedersen-Bjergaard, S 2015, On-chip electromembrane extraction for monitoring drug metabolism in real time by electrospray ionization mass spectrometry. i A Van Schepdael (red.), Microchip Capillary Electrophoresis Protocols. bind 1274, Humana Press, Methods in molecular biology (Clifton, N.J.), s. 171-82. https://doi.org/10.1007/978-1-4939-2353-3_15

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