Osteopontin deficiency dampens the pro-atherogenic effect of uraemia

Tanja Xenia Pedersen; Marie Madsen; Nanna Maria Junker Nielsen; Christina Christoffersen; Jonas Vikeså; Susanne Bro; Anna Hultgårdh-Nilsson; Lars Bo Nielsen

doi:10.1093/cvr/cvt049

Osteopontin deficiency dampens the pro-atherogenic effect of uraemia

Tanja Xenia Pedersen, Marie Madsen, Nanna Maria Junker Nielsen, Christina Christoffersen, Jonas Vikeså, Susanne Bro, Anna Hultgårdh-Nilsson, Lars Bo Nielsen

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

17 Citationer (Scopus)

Abstract

Uraemia is a strong risk factor for cardiovascular disease. Osteopontin (OPN) is highly expressed in aortas of uraemic apolipoprotein E knockout (E KO) mice. OPN affects key atherogenic processes, i.e. inflammation and phenotypic modulation of smooth muscle cells (SMCs). We explored the role of OPN on vascular pathology in uraemic mice.

Originalsprog	Engelsk
Tidsskrift	Cardiovascular Research
Vol/bind	98
Udgave nummer	3
Sider (fra-til)	352-9
Antal sider	8
ISSN	0008-6363
DOI	https://doi.org/10.1093/cvr/cvt049
Status	Udgivet - 1 jun. 2013

Adgang til dokumentet

10.1093/cvr/cvt049

Citationsformater

Osteopontin deficiency dampens the pro-atherogenic effect of uraemia. / Pedersen, Tanja Xenia; Madsen, Marie; Nielsen, Nanna Maria Junker; Christoffersen, Christina; Vikeså, Jonas; Bro, Susanne; Hultgårdh-Nilsson, Anna; Nielsen, Lars Bo.

I: Cardiovascular Research, Bind 98, Nr. 3, 01.06.2013, s. 352-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

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AU - Pedersen, Tanja Xenia

AU - Madsen, Marie

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AU - Vikeså, Jonas

AU - Bro, Susanne

AU - Hultgårdh-Nilsson, Anna

AU - Nielsen, Lars Bo

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