Abstract
Lactate released from skeletal muscle during high-intensity exercise gives rise to a surge in circulating lactate-derived pseudo-dipeptide metabolites including N-lactoyl-phenylalanine (Lac-Phe). In a recent Nature paper, Li et al. use genetic and pharmacological evidence to now propose Lac-Phe to be an “exercise hormone” that suppresses appetite and obesity.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Cell Metabolism |
| Vol/bind | 34 |
| Udgave nummer | 8 |
| Sider (fra-til) | 1085-1087 |
| Antal sider | 3 |
| ISSN | 1550-4131 |
| DOI |
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| Status | Udgivet - 2022 |
Bibliografisk note
Funding Information:The Novo Nordisk Foundation Center for Basic Metabolic Research is an independent Research Center, based at the University of Copenhagen, Denmark, and partially funded by an unconditional donation from the Novo Nordisk Foundation ( https://cbmr.ku.dk/ ) (grant number NNF18CC0034900 ). Cartoon was prepared using https://biorender.com/ .
Funding Information:
The Novo Nordisk Foundation Center for Basic Metabolic Research is an independent Research Center, based at the University of Copenhagen, Denmark, and partially funded by an unconditional donation from the Novo Nordisk Foundation (https://cbmr.ku.dk/) (grant number NNF18CC0034900). Cartoon was prepared using https://biorender.com/. C.C. is a co-founder of Ousia Pharma ApS, and T.W.S is a co-founder and chief scientific godfather of Embark Biotech Aps and Warbug Oncology ApS.
Publisher Copyright:
© 2022 Elsevier Inc.