TY - JOUR
T1 - Paleo-eskimo mtDNA genome reveals matrilineal discontinuity in Greenland
AU - Gilbert, Marcus Thomas Pius
AU - Kivisild, Toomas
AU - Grønnow, Bjarne
AU - Andersen, Pernille K
AU - Metspalu, Ene
AU - Reidla, Maere
AU - Tamm, Erika
AU - Axelsson, Erik
AU - Götherström, Anders
AU - Campos, Paula F
AU - Rasmussen, Morten
AU - Metspalu, Mait
AU - Higham, Thomas F G
AU - Schwenninger, Jean-Luc
AU - Nathan, Roger
AU - De Hoog, Cees-Jan
AU - Koch, Anders
AU - Møller, Lone Nukarak
AU - Andreasen, Claus
AU - Meldgaard, Morten
AU - Villems, Richard
AU - Bendixen, Christian
AU - Willerslev, Eske
N1 - Keywords: Asian Continental Ancestry Group; DNA, Mitochondrial; Emigration and Immigration; Female; Genetics, Population; Genome, Mitochondrial; Greenland; Hair; Haplotypes; History, Ancient; Humans; Indians, North American; Inuits; Male; Molecular Sequence Data; Polymorphism, Single Nucleotide; Sequence Analysis, DNA
PY - 2008
Y1 - 2008
N2 - The Paleo-Eskimo Saqqaq and Independence I cultures, documented from archaeological remains in Northern Canada and Greenland, represent the earliest human expansion into the New World's northern extremes. However, their origin and genetic relationship to later cultures are unknown. We sequenced a mitochondrial genome from a Paleo-Eskimo human by using 3400-to 4500-year-old frozen hair excavated from an early Greenlandic Saqqaq settlement. The sample is distinct from modern Native Americans and Neo-Eskimos, falling within haplogroup D2a1, a group previously observed among modern Aleuts and Siberian Sireniki Yuit. This result suggests that the earliest migrants into the New World's northern extremes derived from populations in the Bering Sea area and were not directly related to Native Americans or the later Neo-Eskimos that replaced them.
AB - The Paleo-Eskimo Saqqaq and Independence I cultures, documented from archaeological remains in Northern Canada and Greenland, represent the earliest human expansion into the New World's northern extremes. However, their origin and genetic relationship to later cultures are unknown. We sequenced a mitochondrial genome from a Paleo-Eskimo human by using 3400-to 4500-year-old frozen hair excavated from an early Greenlandic Saqqaq settlement. The sample is distinct from modern Native Americans and Neo-Eskimos, falling within haplogroup D2a1, a group previously observed among modern Aleuts and Siberian Sireniki Yuit. This result suggests that the earliest migrants into the New World's northern extremes derived from populations in the Bering Sea area and were not directly related to Native Americans or the later Neo-Eskimos that replaced them.
U2 - 10.1126/science.1159750
DO - 10.1126/science.1159750
M3 - Journal article
C2 - 18511654
VL - 320
SP - 1787
EP - 1789
JO - Science
JF - Science
SN - 0036-8075
IS - 5884
ER -