Abstract
Background: Immune checkpoint inhibitors (ICI) have improved cancer treatment, but this treatment can lead to immune-related adverse events (irAEs). Effective patient and caregiver education is essential to better management of irAEs and improved treatment outcomes.
Objective: This integrative review aimed to elucidate how patient education on ICI efficacy and toxicity management affects patients with cancer and their family caregivers' self-efficacy and self-management when dealing with irAEs.
Methods: An integrative review was conducted. EMBASE, MEDLINE, CINAHL, PsycINFO, and Scopus were searched for original research articles. Studies on educational interventions related to ICI and how it affects self-efficacy and self-management of irAEs were included. Data were analyzed using thematic analysis.
Results: Of 4182 references screened; seven studies were included. Three themes emerged: (a) Feasibility of various strategies in patient education, (b) The effect of patient education on self-efficacy, and (c) Determinants to improve self-management of irAEs.
Conclusion: While traditional patient education methods (oral and/or written information) remain valuable, integrating digital technologies is promising to enhance understanding of ICI. Patient education, especially when combined with follow-up, can improve health-related quality of life and self-efficacy. However, health literacy plays a critical role in treatment and management of irAEs, emphasizing the need for personalized education approaches.
Objective: This integrative review aimed to elucidate how patient education on ICI efficacy and toxicity management affects patients with cancer and their family caregivers' self-efficacy and self-management when dealing with irAEs.
Methods: An integrative review was conducted. EMBASE, MEDLINE, CINAHL, PsycINFO, and Scopus were searched for original research articles. Studies on educational interventions related to ICI and how it affects self-efficacy and self-management of irAEs were included. Data were analyzed using thematic analysis.
Results: Of 4182 references screened; seven studies were included. Three themes emerged: (a) Feasibility of various strategies in patient education, (b) The effect of patient education on self-efficacy, and (c) Determinants to improve self-management of irAEs.
Conclusion: While traditional patient education methods (oral and/or written information) remain valuable, integrating digital technologies is promising to enhance understanding of ICI. Patient education, especially when combined with follow-up, can improve health-related quality of life and self-efficacy. However, health literacy plays a critical role in treatment and management of irAEs, emphasizing the need for personalized education approaches.
| Originalsprog | Engelsk |
|---|---|
| Artikelnummer | e70100 |
| Tidsskrift | Psycho-Oncology |
| Vol/bind | 34 |
| Udgave nummer | 3 |
| ISSN | 1057-9249 |
| DOI | |
| Status | Udgivet - 2025 |
Bibliografisk note
Funding Information:The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by AgeCare\u2014Academy of Geriatric Cancer Research, The Region of Southern Denmark, and Immunotox Research Center of Southern Denmark (ICiTox), Odense University Hospital. Funding:
Publisher Copyright:
© 2025 The Author(s). Psycho-Oncology published by John Wiley & Sons Ltd.