Abstract
Palmar-plantar erythrodysesthesia (PPE, hand-foot syndrome) is a relatively frequent cutaneous toxicity related to antineoplastic treatment with e.g. fluorouracil, capecitabine, and liposomal doxorubicin. It usually presents as paresthesia and painful erythema of the palms and soles and may lead to ulceration of the skin. The symptoms are dose-dependent, and the condition may be dose-limiting. Two cases of chemotherapy-associated PPE are presented.
| Bidragets oversatte titel | Plantar-palmar erythrodysesthesia. A new and relatively frequent side effect in antineoplastic treatment |
|---|---|
| Originalsprog | Dansk |
| Tidsskrift | Ugeskrift for Laeger |
| Vol/bind | 165 |
| Udgave nummer | 33 |
| Sider (fra-til) | 3161-2 |
| Antal sider | 2 |
| ISSN | 0041-5782 |
| Status | Udgivet - 11 aug. 2003 |
Emneord
- Antimetabolites, Antineoplastic/adverse effects
- Antineoplastic Agents/adverse effects
- Capecitabine
- Deoxycytidine/adverse effects
- Dose-Response Relationship, Drug
- Doxorubicin/adverse effects
- Drug Eruptions/etiology
- Female
- Fluorouracil/adverse effects
- Foot Dermatoses/chemically induced
- Hand Dermatoses/chemically induced
- Humans
- Male
- Middle Aged
- Syndrome