Platelet count kinetics following interruption of antiretroviral treatment

Eva Zetterberg, Jacqueline Neuhaus, Jason V Baker, Charurut Somboonwit, Josep M Llibre, Adrian Palfreeman, Maria Chini, Jens D Lundgren, INSIGHT SMART Study Group

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    11 Citationer (Scopus)

    Abstract

    To investigate the mechanisms of platelet kinetics in the Strategies for Management of Antiretroviral Therapy (SMART) study that demonstrated excess mortality with CD4 guided episodic antiretroviral therapy (ART) drug conservation compared with continuous treatment viral suppression. Follow-up analyses of stored plasma samples demonstrated increased activation of both inflammatory and coagulation pathways after stopping ART.
    OriginalsprogEngelsk
    TidsskriftAIDS (London, England)
    Vol/bind27
    Udgave nummer1
    Sider (fra-til)59-68
    Antal sider10
    DOI
    StatusUdgivet - 2 jan. 2013

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