Polycomb group protein-mediated repression of transcription

Lluís Morey; Kristian Helin

doi:10.1016/j.tibs.2010.02.009

Polycomb group protein-mediated repression of transcription

Lluís Morey, Kristian Helin

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

334 Citationer (Scopus)

Abstract

Udgivelsesdato: 2010-Jun

Originalsprog	Engelsk
Tidsskrift	TIBS -Trends in Biochemical Sciences. Regular ed.
Vol/bind	35
Udgave nummer	6
Sider (fra-til)	323-32
Antal sider	9
ISSN	0968-0004
DOI	https://doi.org/10.1016/j.tibs.2010.02.009
Status	Udgivet - 2010

Bibliografisk note

Adgang til dokumentet

10.1016/j.tibs.2010.02.009

Citationsformater

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title = "Polycomb group protein-mediated repression of transcription",

abstract = "The polycomb group (PcG) proteins are essential for the normal development of multicellular organisms. They form multi-protein complexes that work as transcriptional repressors of several thousand genes controlling differentiation pathways during development. How the PcG proteins work as transcriptional repressors is incompletely understood, but involves post-translational modifications of histones by two major PcG protein complexes: polycomb repressive complex 1 and polycomb repressive complex 2.",

author = "Llu{\'i}s Morey and Kristian Helin",

note = "Keywords: Animals; Histones; Humans; Repressor Proteins; Response Elements; Transcription Factors; Transcription, Genetic",

year = "2010",

doi = "10.1016/j.tibs.2010.02.009",

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T1 - Polycomb group protein-mediated repression of transcription

AU - Morey, Lluís

AU - Helin, Kristian

N1 - Keywords: Animals; Histones; Humans; Repressor Proteins; Response Elements; Transcription Factors; Transcription, Genetic

PY - 2010

Y1 - 2010

N2 - The polycomb group (PcG) proteins are essential for the normal development of multicellular organisms. They form multi-protein complexes that work as transcriptional repressors of several thousand genes controlling differentiation pathways during development. How the PcG proteins work as transcriptional repressors is incompletely understood, but involves post-translational modifications of histones by two major PcG protein complexes: polycomb repressive complex 1 and polycomb repressive complex 2.

AB - The polycomb group (PcG) proteins are essential for the normal development of multicellular organisms. They form multi-protein complexes that work as transcriptional repressors of several thousand genes controlling differentiation pathways during development. How the PcG proteins work as transcriptional repressors is incompletely understood, but involves post-translational modifications of histones by two major PcG protein complexes: polycomb repressive complex 1 and polycomb repressive complex 2.

U2 - 10.1016/j.tibs.2010.02.009

DO - 10.1016/j.tibs.2010.02.009

M3 - Journal article

C2 - 20346678

SN - 0968-0004

VL - 35

SP - 323

EP - 332

JO - TIBS -Trends in Biochemical Sciences. Regular ed.

JF - TIBS -Trends in Biochemical Sciences. Regular ed.

IS - 6

ER -