Polycomb group proteins in cell cycle progression and cancer.

Diego Pasini; Adrian P Bracken; Kristian Helin

Polycomb group proteins in cell cycle progression and cancer.

Diego Pasini, Adrian P Bracken, Kristian Helin

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

82 Citationer (Scopus)

Abstract

Udgivelsesdato: 2004-Apr

Originalsprog	Engelsk
Tidsskrift	Cell Cycle
Vol/bind	3
Udgave nummer	4
Sider (fra-til)	396-400
Antal sider	5
ISSN	1538-4101
Status	Udgivet - 2004
Udgivet eksternt	Ja

Bibliografisk note

Keywords: Animals; Blotting, Western; Cell Cycle; Cell Division; Chromatin; DNA; DNA-Binding Proteins; Drosophila; Gene Expression Regulation; Gene Silencing; Hela Cells; Humans; Models, Biological; Mutation; Neoplasms; Precipitin Tests; Proteins; RNA, Small Interfering; Repressor Proteins; Transcription Factors

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Citationsformater

@article{5859e6e053d111dd8d9f000ea68e967b,

title = "Polycomb group proteins in cell cycle progression and cancer.",

abstract = "Epigenetic deregulation of gene expression is emerging as key mechanism in tumorigenesis. Deregulated activity of the chromatin remodeling Polycomb Repressive Complex 2 (PRC2) has recently been shown to be a frequent event in human tumors. Here we discuss these findings and speculate on the role of the PRC2 complex in controlling gene expression during normal cellular proliferation and cancer development.",

author = "Diego Pasini and Bracken, {Adrian P} and Kristian Helin",

note = "Keywords: Animals; Blotting, Western; Cell Cycle; Cell Division; Chromatin; DNA; DNA-Binding Proteins; Drosophila; Gene Expression Regulation; Gene Silencing; Hela Cells; Humans; Models, Biological; Mutation; Neoplasms; Precipitin Tests; Proteins; RNA, Small Interfering; Repressor Proteins; Transcription Factors",

year = "2004",

language = "English",

volume = "3",

pages = "396--400",

journal = "Cell Cycle",

issn = "1538-4101",

publisher = "Taylor & Francis",

number = "4",

}

TY - JOUR

T1 - Polycomb group proteins in cell cycle progression and cancer.

AU - Pasini, Diego

AU - Bracken, Adrian P

AU - Helin, Kristian

N1 - Keywords: Animals; Blotting, Western; Cell Cycle; Cell Division; Chromatin; DNA; DNA-Binding Proteins; Drosophila; Gene Expression Regulation; Gene Silencing; Hela Cells; Humans; Models, Biological; Mutation; Neoplasms; Precipitin Tests; Proteins; RNA, Small Interfering; Repressor Proteins; Transcription Factors

PY - 2004

Y1 - 2004

N2 - Epigenetic deregulation of gene expression is emerging as key mechanism in tumorigenesis. Deregulated activity of the chromatin remodeling Polycomb Repressive Complex 2 (PRC2) has recently been shown to be a frequent event in human tumors. Here we discuss these findings and speculate on the role of the PRC2 complex in controlling gene expression during normal cellular proliferation and cancer development.

AB - Epigenetic deregulation of gene expression is emerging as key mechanism in tumorigenesis. Deregulated activity of the chromatin remodeling Polycomb Repressive Complex 2 (PRC2) has recently been shown to be a frequent event in human tumors. Here we discuss these findings and speculate on the role of the PRC2 complex in controlling gene expression during normal cellular proliferation and cancer development.

M3 - Journal article

C2 - 14752272

SN - 1538-4101

VL - 3

SP - 396

EP - 400

JO - Cell Cycle

JF - Cell Cycle

IS - 4

ER -