Prolonging peripheral nerve block duration: Current techniques and future perspectives

Mathias Maagaard; Eric Albrecht; Ole Mathiesen

doi:10.1111/aas.70010

Prolonging peripheral nerve block duration: Current techniques and future perspectives

Mathias Maagaard, Eric Albrecht, Ole Mathiesen^*

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Leder › Forskning › peer review

Abstract

Peripheral nerve blocks are widely used for anaesthesia in upper and lower limb surgeries and as part of postoperative multimodal analgesia for various procedures. However, their primary limitation lies in their relatively short duration, which typically ranges from 8 to 14 h when using long-acting local anaesthetics such as ropivacaine or bupivacaine.1 Achieving longer-lasting effects has been a key area of research, leading to the exploration of various adjuncts,1, 2 liposomal bupivacaine3 and catheter-based techniques.

Originalsprog	Engelsk
Artikelnummer	e70010
Tidsskrift	Acta Anaesthesiologica Scandinavica
Vol/bind	69
Udgave nummer	4
Antal sider	4
ISSN	0001-5172
DOI	https://doi.org/10.1111/aas.70010
Status	Udgivet - 2025

Bibliografisk note

Funding Information:
EA received grants from the Swiss Academy for Anesthesia Research (SACAR) and the Swiss National Science Foundation, Bern, Switzerland, to support his clinical research. All other authors declare no competing interests.

Adgang til dokumentet

10.1111/aas.70010Licens: CC BY

FulltextForlagets udgivne version, 242 KBLicens: CC BY

Citationsformater

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abstract = "Peripheral nerve blocks are widely used for anaesthesia in upper and lower limb surgeries and as part of postoperative multimodal analgesia for various procedures. However, their primary limitation lies in their relatively short duration, which typically ranges from 8 to 14 h when using long-acting local anaesthetics such as ropivacaine or bupivacaine.1 Achieving longer-lasting effects has been a key area of research, leading to the exploration of various adjuncts,1, 2 liposomal bupivacaine3 and catheter-based techniques.",

author = "Mathias Maagaard and Eric Albrecht and Ole Mathiesen",

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N2 - Peripheral nerve blocks are widely used for anaesthesia in upper and lower limb surgeries and as part of postoperative multimodal analgesia for various procedures. However, their primary limitation lies in their relatively short duration, which typically ranges from 8 to 14 h when using long-acting local anaesthetics such as ropivacaine or bupivacaine.1 Achieving longer-lasting effects has been a key area of research, leading to the exploration of various adjuncts,1, 2 liposomal bupivacaine3 and catheter-based techniques.

AB - Peripheral nerve blocks are widely used for anaesthesia in upper and lower limb surgeries and as part of postoperative multimodal analgesia for various procedures. However, their primary limitation lies in their relatively short duration, which typically ranges from 8 to 14 h when using long-acting local anaesthetics such as ropivacaine or bupivacaine.1 Achieving longer-lasting effects has been a key area of research, leading to the exploration of various adjuncts,1, 2 liposomal bupivacaine3 and catheter-based techniques.

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