Protocol for assessing the effects of exogenous hormone administration on human postprandial glucose metabolism, appetite sensations, and food intake

Christoffer A. Hagemann*, Lærke S. Gasbjerg, Mikkel B. Christensen, Filip K. Knop

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

12 Downloads (Pure)

Abstract

Here, we present a protocol for a randomized, double-blind, placebo-controlled, crossover trial to evaluate the effects of a continuous intravenous infusion of a native liver-derived hormone, liver-expressed antimicrobial peptide 2 (LEAP2), on postprandial glucose metabolism, appetite and satiety sensations, and ad libitum food intake in humans. We describe the preparation of the exogenous hormone administration and participants. We then detail the liquid mixed meal, ad libitum meal test, and blood sampling procedures for assessing postprandial glucose metabolism and food intake. For complete details on the use and execution of this protocol, please refer to Hagemann et al. (2022).1

OriginalsprogEngelsk
Artikelnummer102070
TidsskriftSTAR Protocols
Vol/bind4
Udgave nummer1
Antal sider10
ISSN2666-1667
DOI
StatusUdgivet - 2023

Bibliografisk note

Publisher Copyright:
© 2023 The Author(s)

Citationsformater