@article{3af5063b747a438daa96d67ef6b3bc0d,
title = "Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion",
abstract = "Expression levels of the urokinase-type plasminogen activator receptor (uPAR) represent an established biomarker for poor prognosis in a variety of human cancers. The objective of the present study was to explore whether noninvasive PET can be used to perform a quantitative assessment of expression levels of uPAR across different human cancer xenograft models in mice and to illustrate the clinical potential of uPAR PET in future settings for individualized therapy.",
keywords = "Animals, Cell Transformation, Neoplastic, Colorectal Neoplasms, Copper Radioisotopes, Female, Gene Expression Regulation, Neoplastic, HT29 Cells, Heterocyclic Compounds, 1-Ring, Humans, Mice, Neoplasm Invasiveness, Oligopeptides, Positron-Emission Tomography, Positron-Emission Tomography and Computed Tomography, Radiochemistry, Receptors, Urokinase Plasminogen Activator",
author = "Morten Persson and Jacob Madsen and S{\o}ren {\O}stergaard and Jensen, {Mette Munk} and J{\o}rgensen, {Jesper Tranekj{\ae}r} and Karina Juhl and Charlotte Lehmann and Michael Ploug and Andreas Kjaer",
year = "2012",
doi = "10.2967/jnumed.110.083386",
language = "English",
volume = "53",
pages = "138--45",
journal = "The Journal of Nuclear Medicine",
issn = "0161-5505",
publisher = "Society of Nuclear Medicine",
number = "1",
}