R package for Sex-of-Parent-specific Transmission Ratio Distortion

Lam Opal Huang

R package for Sex-of-Parent-specific Transmission Ratio Distortion

Lam Opal Huang (Producent)

Publikation: Bidrag der ikke har en tekstform › Softwareprogram › Forskning

Abstract

Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.

Originalsprog	Engelsk
Publikationsdato	2015
Udgivelsessted	Canada
Udgave	v2
Publikationsmedier	Web
Status	Udgivet - 2015

Andre filer og links

https://cran.r-project.org/web/packages/TRD/index.html

Citationsformater

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title = "R package for Sex-of-Parent-specific Transmission Ratio Distortion",

abstract = "Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.",

author = "Huang, {Lam Opal}",

year = "2015",

language = "English",

publisher = "CRAN - The Comprehensive R Archive Network",

edition = "v2",

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T1 - R package for Sex-of-Parent-specific Transmission Ratio Distortion

A2 - Huang, Lam Opal

PY - 2015

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N2 - Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.

AB - Transmission Ratio Distortion (TRD) is a genetic phenomenon where the two alleles from either parent are not transmitted to the offspring at the expected 1:1 ratio under Mendelian inheritance, leading to spurious signals in genetic association studies. Functions in this package are developed to account for this phenomenon using loglinear model and Transmission Disequilibrium Test (TDT). Some population information can also be calculated.

UR - https://cran.r-project.org/web/packages/TRD/index.html

M3 - Computer programme

PB - CRAN - The Comprehensive R Archive Network

CY - Canada

ER -