Reduced prevalence of early preterm delivery in women with Type 1 diabetes and microalbuminuria--possible effect of early antihypertensive treatment during pregnancy

L R Nielsen, Claus Kragh-Müller, P Damm, E R Mathiesen

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    45 Citationer (Scopus)

    Abstract

    In normotensive women with Type 1 diabetes and microalbuminuria we previously found preterm delivery (<34 weeks) in 23% of the pregnancies. Antihypertensive treatment was initiated in late pregnancy when preeclampsia was diagnosed and diastolic blood pressure > 90 mmHg. From April 2000 our routine was changed and early antihypertensive treatment with methyldopa was initiated if antihypertensive treatment was given prior to pregnancy, if urinary albumin excretion (UAE) was > 2 g/24 h, or blood pressure > 140/90 mmHg. The present study describes the impact of this more aggressive antiypertensive treatment in the prevalence of preterm delivery.
    OriginalsprogEngelsk
    TidsskriftDiabetic Medicine
    Vol/bind23
    Udgave nummer4
    Sider (fra-til)426-31
    Antal sider6
    ISSN0742-3071
    DOI
    StatusUdgivet - 1 apr. 2006

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