Reduction of salivary mutans streptococci in orthodontic patients during daily consumption of yoghurt containing probiotic bacteria

Sule Kavaloglu Cildir; Derya Germec; Nuket Sandalli; Fulya Isik Ozdemir; Tulin Arun; Svante Twetman; Esber Caglar

doi:10.1093/ejo/cjn108

Reduction of salivary mutans streptococci in orthodontic patients during daily consumption of yoghurt containing probiotic bacteria

Sule Kavaloglu Cildir, Derya Germec, Nuket Sandalli, Fulya Isik Ozdemir, Tulin Arun, Svante Twetman, Esber Caglar

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

117 Citationer (Scopus)

Abstract

Udgivelsesdato: 2009-Aug

Originalsprog	Engelsk
Tidsskrift	European Journal of Orthodontics
Vol/bind	31
Udgave nummer	4
Sider (fra-til)	407-11
Antal sider	4
ISSN	0141-5387
DOI	https://doi.org/10.1093/ejo/cjn108
Status	Udgivet - 2009

Bibliografisk note

Keywords: Adolescent; Bifidobacterium; Child; Colony Count, Microbial; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Humans; Lactobacillus; Male; Orthodontic Appliances; Probiotics; Saliva; Streptococcus mutans; Yogurt

Adgang til dokumentet

10.1093/ejo/cjn108

Citationsformater

@article{c5c88fc02ce611df8ed1000ea68e967b,

title = "Reduction of salivary mutans streptococci in orthodontic patients during daily consumption of yoghurt containing probiotic bacteria",

abstract = "Previous studies have suggested that probiotic supplements in dairy products may affect the oral microbial ecology, but the effect in orthodontic patients has not previously been reported. The aim of the present study was to examine whether short-term consumption of fruit yogurt containing probiotic bifidobacteria would affect the levels of salivary mutans streptococci and lactobacilli in patients with fixed orthodontic appliances. A double-blind, randomized crossover study was performed and 24 healthy adolescents (12-16 years) undergoing orthodontic treatment were followed over four periods. During periods 2 and 4 (2 weeks each), the subjects ingested 200 g fruit yogurt containing Bifidobacterium animalis subsp. lactis DN-173010 (2 x 10(8) colony forming units/g) once daily or a control yogurt without viable bacteria. Periods 1 and 3 were run-in and wash-out periods of 1 and 6 weeks, respectively. Salivary mutans streptococci and lactobacilli were enumerated with chair-side kits before and after the yogurt consumption periods. Pre- and post-treatment values within each regimen were compared with a two-tailed marginal homogeneity test for categorical data. A statistically significant reduction of salivary mutans streptococci was recorded after probiotic yogurt consumption (P < 0.05), which was in contrast to the control yogurt. No significant alterations of the salivary lactobacilli counts were observed. Short-term daily consumption of fruit yogurt containing Bifidobacterium animalis subsp. lactis DN-173010 may reduce the levels of mutans streptococci in saliva during orthodontic treatment with fixed appliances.",

author = "Cildir, {Sule Kavaloglu} and Derya Germec and Nuket Sandalli and Ozdemir, {Fulya Isik} and Tulin Arun and Svante Twetman and Esber Caglar",

note = "Keywords: Adolescent; Bifidobacterium; Child; Colony Count, Microbial; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Humans; Lactobacillus; Male; Orthodontic Appliances; Probiotics; Saliva; Streptococcus mutans; Yogurt",

year = "2009",

doi = "10.1093/ejo/cjn108",

language = "English",

volume = "31",

pages = "407--11",

journal = "European Journal of Orthodontics",

issn = "0141-5387",

publisher = "Oxford University Press",

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TY - JOUR

T1 - Reduction of salivary mutans streptococci in orthodontic patients during daily consumption of yoghurt containing probiotic bacteria

AU - Cildir, Sule Kavaloglu

AU - Germec, Derya

AU - Sandalli, Nuket

AU - Ozdemir, Fulya Isik

AU - Arun, Tulin

AU - Twetman, Svante

AU - Caglar, Esber

N1 - Keywords: Adolescent; Bifidobacterium; Child; Colony Count, Microbial; Cross-Over Studies; Double-Blind Method; Female; Follow-Up Studies; Humans; Lactobacillus; Male; Orthodontic Appliances; Probiotics; Saliva; Streptococcus mutans; Yogurt

PY - 2009

Y1 - 2009

N2 - Previous studies have suggested that probiotic supplements in dairy products may affect the oral microbial ecology, but the effect in orthodontic patients has not previously been reported. The aim of the present study was to examine whether short-term consumption of fruit yogurt containing probiotic bifidobacteria would affect the levels of salivary mutans streptococci and lactobacilli in patients with fixed orthodontic appliances. A double-blind, randomized crossover study was performed and 24 healthy adolescents (12-16 years) undergoing orthodontic treatment were followed over four periods. During periods 2 and 4 (2 weeks each), the subjects ingested 200 g fruit yogurt containing Bifidobacterium animalis subsp. lactis DN-173010 (2 x 10(8) colony forming units/g) once daily or a control yogurt without viable bacteria. Periods 1 and 3 were run-in and wash-out periods of 1 and 6 weeks, respectively. Salivary mutans streptococci and lactobacilli were enumerated with chair-side kits before and after the yogurt consumption periods. Pre- and post-treatment values within each regimen were compared with a two-tailed marginal homogeneity test for categorical data. A statistically significant reduction of salivary mutans streptococci was recorded after probiotic yogurt consumption (P < 0.05), which was in contrast to the control yogurt. No significant alterations of the salivary lactobacilli counts were observed. Short-term daily consumption of fruit yogurt containing Bifidobacterium animalis subsp. lactis DN-173010 may reduce the levels of mutans streptococci in saliva during orthodontic treatment with fixed appliances.

AB - Previous studies have suggested that probiotic supplements in dairy products may affect the oral microbial ecology, but the effect in orthodontic patients has not previously been reported. The aim of the present study was to examine whether short-term consumption of fruit yogurt containing probiotic bifidobacteria would affect the levels of salivary mutans streptococci and lactobacilli in patients with fixed orthodontic appliances. A double-blind, randomized crossover study was performed and 24 healthy adolescents (12-16 years) undergoing orthodontic treatment were followed over four periods. During periods 2 and 4 (2 weeks each), the subjects ingested 200 g fruit yogurt containing Bifidobacterium animalis subsp. lactis DN-173010 (2 x 10(8) colony forming units/g) once daily or a control yogurt without viable bacteria. Periods 1 and 3 were run-in and wash-out periods of 1 and 6 weeks, respectively. Salivary mutans streptococci and lactobacilli were enumerated with chair-side kits before and after the yogurt consumption periods. Pre- and post-treatment values within each regimen were compared with a two-tailed marginal homogeneity test for categorical data. A statistically significant reduction of salivary mutans streptococci was recorded after probiotic yogurt consumption (P < 0.05), which was in contrast to the control yogurt. No significant alterations of the salivary lactobacilli counts were observed. Short-term daily consumption of fruit yogurt containing Bifidobacterium animalis subsp. lactis DN-173010 may reduce the levels of mutans streptococci in saliva during orthodontic treatment with fixed appliances.

U2 - 10.1093/ejo/cjn108

DO - 10.1093/ejo/cjn108

M3 - Journal article

C2 - 19193706

SN - 0141-5387

VL - 31

SP - 407

EP - 411

JO - European Journal of Orthodontics

JF - European Journal of Orthodontics

IS - 4

ER -