Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies

Shravankumar Kankala; Ranjith Kumar Kankala; Prasad Gundepaka; Niranjan Thota; Srinivas Nerella; Mohan Rao Gangula; Hanmanthu Guguloth; Mukkanti Kagga; Ravinder Vadde; Chandra Sekhar Vasam

doi:10.1016/j.bmcl.2012.12.101

Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies

Shravankumar Kankala, Ranjith Kumar Kankala, Prasad Gundepaka, Niranjan Thota, Srinivas Nerella, Mohan Rao Gangula, Hanmanthu Guguloth, Mukkanti Kagga, Ravinder Vadde, Chandra Sekhar Vasam

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

117 Citationer (Scopus)

Abstract

Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their efficiency in in vivo analgesic and anti-inflammatory activity was described. A comparison of structure-activity relationship for there compounds was also emphasized.

Originalsprog	Engelsk
Tidsskrift	Bioorganic & Medicinal Chemistry Letters
Vol/bind	23
Udgave nummer	5
Sider (fra-til)	1306-9
Antal sider	4
ISSN	0960-894X
DOI	https://doi.org/10.1016/j.bmcl.2012.12.101
Status	Udgivet - 1 mar. 2013

Adgang til dokumentet

10.1016/j.bmcl.2012.12.101

Citationsformater

Kankala, S., Kankala, R. K., Gundepaka, P., Thota, N., Nerella, S., Gangula, M. R., Guguloth, H., Kagga, M., Vadde, R., & Vasam, C. S. (2013). Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies. Bioorganic & Medicinal Chemistry Letters, 23(5), 1306-9. https://doi.org/10.1016/j.bmcl.2012.12.101

Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies. / Kankala, Shravankumar; Kankala, Ranjith Kumar; Gundepaka, Prasad et al.
I: Bioorganic & Medicinal Chemistry Letters, Bind 23, Nr. 5, 01.03.2013, s. 1306-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Kankala, S, Kankala, RK, Gundepaka, P, Thota, N, Nerella, S, Gangula, MR, Guguloth, H, Kagga, M, Vadde, R & Vasam, CS 2013, 'Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies', Bioorganic & Medicinal Chemistry Letters, bind 23, nr. 5, s. 1306-9. https://doi.org/10.1016/j.bmcl.2012.12.101

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abstract = "Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their efficiency in in vivo analgesic and anti-inflammatory activity was described. A comparison of structure-activity relationship for there compounds was also emphasized.",

keywords = "Analgesics, Anti-Inflammatory Agents, Benzimidazoles, Isoxazoles, Structure-Activity Relationship, Journal Article",

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AU - Kankala, Shravankumar

AU - Kankala, Ranjith Kumar

AU - Gundepaka, Prasad

AU - Thota, Niranjan

AU - Nerella, Srinivas

AU - Gangula, Mohan Rao

AU - Guguloth, Hanmanthu

AU - Kagga, Mukkanti

AU - Vadde, Ravinder

AU - Vasam, Chandra Sekhar

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AB - Regioselective synthesis of isoxazole-mercaptobenzimidazole hybrids and their efficiency in in vivo analgesic and anti-inflammatory activity was described. A comparison of structure-activity relationship for there compounds was also emphasized.

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KW - Anti-Inflammatory Agents

KW - Benzimidazoles

KW - Isoxazoles

KW - Structure-Activity Relationship

KW - Journal Article

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DO - 10.1016/j.bmcl.2012.12.101

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SN - 0960-894X

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JO - Bioorganic & Medicinal Chemistry Letters

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