@article{3cc05990bd884682b145c17865da3ee1,
title = "Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis",
abstract = "Cartilage oligomeric matrix protein (COMP) is a structural component of cartilage, where it catalyzes collagen fibrillogenesis. Elevated amounts of COMP are found in serum during increased turnover of cartilage associated with active joint disease, such as rheumatoid arthritis (RA) and osteoarthritis (OA). This study was undertaken to investigate the ability of COMP to regulate complement, a capacity that has previously been shown for some other cartilage proteins.",
keywords = "Adult, Aged, Aged, 80 and over, Arthritis, Rheumatoid, Biological Markers, Case-Control Studies, Complement C1q, Complement C3b, Complement C9, Complement System Proteins, Extracellular Matrix Proteins, Female, Glycoproteins, Humans, Male, Mannose-Binding Lectin, Middle Aged, Osteoarthritis, Properdin, Synovial Fluid",
author = "Happonen, {Kaisa E} and Tore Saxne and Anders Aspberg and Matthias M{\"o}rgelin and Dick Heineg{\aa}rd and Blom, {Anna M}",
note = "Copyright {\textcopyright} 2010 by the American College of Rheumatology.",
year = "2010",
doi = "10.1002/art.27720",
language = "English",
volume = "62",
pages = "3574--83",
journal = "Arthritis & Rheumatism",
issn = "0004-3591",
publisher = "Wiley",
number = "12",
}