Relationship between common lipoprotein lipase gene sequence variants, hyperinsulinemia, and risk of ischemic heart disease: A population-based study

Jørgen Jeppesen, Tine Willum Hansen, Christian Torp-Pedersen, Sten Madsbad, Hans Ibsen, Torben Jørgensen, Mogens Fenger

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10 Citationer (Scopus)

Abstract

Hyperinsulinemia and lipoprotein lipase (LPL) are important determinants of fasting and postprandial plasma triglyceride levels. High insulin and high triglyceride levels are associated with an increased risk of ischemic heart disease (IHD). This study aimed to find out whether common LPL gene sequence variants could change the relationship between insulin and IHD.
OriginalsprogEngelsk
TidsskriftAtherosclerosis
Vol/bind211
Udgave nummer2
Sider (fra-til)506-11
Antal sider6
ISSN0021-9150
DOI
StatusUdgivet - 1 aug. 2010

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