Resistance exercise-induced hypertrophy: A potential role for rapamycin-insensitive mTOR

Riki Ogasawara*, Thomas Elbenhardt Jensen, Craig A Goodman, Troy A Hornberger

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftReviewForskningpeer review

35 Citationer (Scopus)

Abstract

The mechanistic target of rapamycin (mTOR) exerts both rapamycin-sensitive and rapamycin-insensitive signaling events, and the rapamycin-sensitive components of mTOR signaling have been widely implicated in the pathway through which resistance exercise induces skeletal muscle hypertrophy. This review explores the hypothesis that rapamycin-insensitive components of mTOR signaling also contribute to this highly important process.

Summary: This review examines whether both rapamycin-sensitive, and rapamycin-insensitive, components of mTOR signaling contribute to the hypertrophic effects of resistance exercise.

OriginalsprogEngelsk
TidsskriftExercise and Sport Sciences Reviews
Vol/bind47
Udgave nummer3
Sider (fra-til)188-194
ISSN0091-6331
DOI
StatusUdgivet - 2019

Bibliografisk note

CURIS 2019 NEXS 249

Emneord

  • Det Natur- og Biovidenskabelige Fakultet

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