Screening for affinity ligands for biopurification

Phaedria M. St. Hilaire*, M. Meldal

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Abstract

The worldwide market for biopharmaceuticals and the number of new pro tein drugs are rapidly increasing. For every new drug a new purification process must be developed. For some drugs this can be achieved by modify ing the process parameters used in an existing process whereas for other drugs a whole new process must be developed. This can be a challenging and very costly process, which in the worst case delays the product launch. The problem can be largely overcome by implementing affinity chromatography. However, there is a need for affinity ligands for purifying non-immunoglob ulins. We present here an overview of technologies and suppliers within the field of development of affinity chromatography media.

OriginalsprogEngelsk
TidsskriftBio Tech International
Vol/bind18
Udgave nummer5
Sider (fra-til)12-16
Antal sider5
StatusUdgivet - okt. 2006
Udgivet eksterntJa

Citationsformater