Abstract
Background: Sedentary lifestyle and unhealthy diet combined with overweight are risk factors for type 2 diabetes (T2D). Lifestyle interventions with weight-loss are effective in T2D-prevention, but unsuccessful completion and chronic stress may hinder efficacy. Determinants of chronic stress and premature cessation at the start of the 3-year PREVIEW study were examined. Methods: Baseline Quality of Life (QoL), social support, primary care utilization, and mood were examined as predictors of intervention cessation and chronic stress for participants aged 25 to 70 with prediabetes (n = 2,220). Moderating effects of sex and socio-economic status (SES) and independence of predictor variables of BMI were tested. Results: Participants with children, women, and higher SES quitted intervention earlier than those without children, lower SES, and men. Lower QoL, lack of family support, and primary care utilization were associated with cessation. Lower QoL and higher mood disturbances were associated with chronic stress. Predictor variables were independent (p ≤.001) from BMI, but moderated by sex and SES. Conclusions: Policy-based strategy in public health should consider how preventive interventions may better accommodate different individual states and life situations, which could influence intervention completion. Intervention designs should enable in-built flexibility in delivery enabling response to individual needs. Trial registration: ClinicalTrials.gov Identifier: NCT01777893.
Originalsprog | Engelsk |
---|---|
Artikelnummer | 1666 |
Tidsskrift | BMC Public Health |
Vol/bind | 23 |
Udgave nummer | 1 |
Antal sider | 20 |
ISSN | 1471-2458 |
DOI | |
Status | Udgivet - 2023 |
Bibliografisk note
Funding Information:Open Access funding enabled and organized by Projekt DEAL. The EU framework programme 7 (FP7/2007–2013) grant agreement # 312057. National Health and Medical Research Council – EU Collaborative Grant, AUS 8, ID 1067711. The Glycemic Index Foundation Australia through royalties to the University of Sydney. The NZ Health Research Council (14/191) and University of Auckland Faculty Research Development Fund. The Cambridge Weight Plan donated all products for the 8-week LED period. The Danish Agriculture & Food Council. The Danish Meat and Research Institute. National Institute for Health Research Biomedical Research Centre (NIHR BRC) (UK). Biotechnology and Biological Sciences Research Council (BBSRC) (UK). Engineering and Physical Sciences Research Council (EPSRC) (UK). Nutritics (Dublin) donated all dietary analyses software used by UNOTT. Juho Vainio Foundation (FIN), Academy of Finland (grant numbers: 272376, 314383, 266286, 314135), Finnish Medical Foundation, Gyllenberg Foundation, Novo Nordisk Foundation, Finnish Diabetes Research Foundation, University of Helsinki, Government Research Funds for Helsinki University Hospital (FIN), Jenny and Antti Wihuri Foundation (FIN), Emil Aaltonen Foundation (FIN).
Funding Information:
PREVIEW Study concept and design: Edith Feskens, Wageningen University, Netherlands. PREMIT behaviour modification intervention: Daniela Kahlert and Annelie Unyi-Reicherz (University of Stuttgart, Germany). The following contributors listed below assisted in conduct of the trial during recruitment, intervention and/or data collection: University of Copenhagen, Denmark: Ulla Skovbæch Pedersen, Marianne Juhl Hansen, Bettina Belmann Mirasola, Maria Roed Andersen, Anne Wengler, Lene Stevner, Jane Jørgensen, Sofie Skov Frost, Eivind Bjørås, Grith Møller, Lone Vestergaard Nielsen. University of Helsinki, Finland: Saara Grönholm (née Kettunen), Karoliina Himanen, Heini Hyvärinen, Martta Jalavisto (née Nieminen), Heidi Jokinen, Laura Kainu (née Korpipää), Pauliina Kokkonen, Liisi Korhonen, Tiia Kunnas, Elina Malkamäki, Pihla Mäkinen, Tuulia Onali (née Ingman), Tiina Pellinen, Kirsi Pietiläinen, Heli Pikkarainen, Sanna Ritola, Heikki Tikkanen, Sonja Toijonen, Jaana Valkeapää. University of Nottingham, United Kingdom: Liz Simpson, Moira Taylor, Shelley Archer, Natalie Bailey-Flitter, Nicky Gilbert, Laura Helm, Sally Maitland, Melanie Marshall, Theresa Mellor, Grace Miller, Seodhna Murphy, Vicky Newman, Amy Postles, Jakki Pritchard, Maria Papageorgiou, Cheryl Percival, Clare Randall, Sue Smith, Sarah Skirrow. University of Navarra, Spain: Blanca Martinez de Morentin Aldabe, María Hernández Ruiz de Eguilaz, Salomé Pérez Diez, Rodrigo San-Cristobal, Maria dels Angels Batlle, Laura Moreno-Galarraga, Alejandro Fernández-Montero, Marian Nuin, Javier Baquedano, Maria Eugenia Ursúa, Francisco Javier Martinez Jarauta, Pilar Buil, Lourdes Dorronsoro, Juana María Vizcay, Teodoro Durá-Travé, and all general practitioners and nurses from the Navarra Health Services who collaborated in the recruitment of the participants. Medical University of Sofia, Bulgaria: Nadka Boyadjieva, Pavlina Gateva-Andreeva, Georgi Bogdanov, Galina Dobrevska. University of Auckland, New Zealand: Amy Liu, Lindsay Plank, Anne-Thea McGill, Madhavi Bollineni, Clarence Vivar, Kelly Storey, Nicholas Gant, Jonathon Woodhead, University of Sydney, Australia: Kylie Simpson, Michele Whittle, Kirstine Bell, Shannon Brodie, Jessica Burk. We want to acknowledge all the additional people who have worked and are currently working for PREVIEW including trainees, post- and undergraduate students. Finally, a respectful thank you to all the study participants that participated in PREVIEW.
Publisher Copyright:
© 2023, BioMed Central Ltd., part of Springer Nature.