Solid-phase synthesis of 3-amino-2-pyrazolines

Lars O. Lyngsø; John Nielsen

doi:10.1016/S0040-4039(98)01158-7

Solid-phase synthesis of 3-amino-2-pyrazolines

Lars O. Lyngsø, John Nielsen^*

^*Corresponding author af dette arbejde

LUKKET: Natural Products and Peptides

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

13 Citationer (Scopus)

Abstract

The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.

Originalsprog	Engelsk
Tidsskrift	Tetrahedron Letters
Vol/bind	39
Udgave nummer	32
Sider (fra-til)	5845-5848
Antal sider	4
ISSN	0040-4039
DOI	https://doi.org/10.1016/S0040-4039(98)01158-7
Status	Udgivet - 6 aug. 1998

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10.1016/S0040-4039(98)01158-7

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Citationsformater

@article{16f344785673472fa2f936aff4e52f97,

title = "Solid-phase synthesis of 3-amino-2-pyrazolines",

abstract = "The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.",

author = "Lyngs{\o}, {Lars O.} and John Nielsen",

year = "1998",

month = aug,

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doi = "10.1016/S0040-4039(98)01158-7",

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journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Solid-phase synthesis of 3-amino-2-pyrazolines

AU - Lyngsø, Lars O.

AU - Nielsen, John

PY - 1998/8/6

Y1 - 1998/8/6

N2 - The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.

AB - The development of a solid-phase synthesis of 3-amino-2-pyrazolines is described. Conjugate addition of hydrazines to α,β-unsaturated nitriles followed by cyclization yields 3-amino-2-pyrazolines. Acylation or sulfonation of the free amino-group yields a 24 member library of 3-amino-2- pyrazolines.

U2 - 10.1016/S0040-4039(98)01158-7

DO - 10.1016/S0040-4039(98)01158-7

M3 - Journal article

AN - SCOPUS:0032490961

SN - 0040-4039

VL - 39

SP - 5845

EP - 5848

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 32

ER -