ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy

Paul W Armstrong; Hany Siha; Yuling Fu; Cynthia M Westerhout; Ph Gabriel Steg; Stefan K James; Robert F Storey; Jay Horrow; Hugo Katus; Peter Clemmensen; Robert A Harrington; Lars Wallentin

doi:10.1161/CIRCULATIONAHA.111.047530

ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy

Paul W Armstrong, Hany Siha, Yuling Fu, Cynthia M Westerhout, Ph Gabriel Steg, Stefan K James, Robert F Storey, Jay Horrow, Hugo Katus, Peter Clemmensen, Robert A Harrington, Lars Wallentin

Institut for Klinisk Medicin

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

39 Citationer (Scopus)

Abstract

Ticagrelor, when compared with clopidogrel, reduced the 12-month risk of vascular death/myocardial infarction and stroke in patients with ST-elevation acute coronary syndromes intended to undergo primary percutaneous coronary intervention in the PLATelet inhibition and patient Outcomes (PLATO) trial. This prespecified ECG substudy explored whether ticagrelor's association with vascular death and myocardial infarction within 1 year would be amplified by (1) the extent of baseline ST shift and (2) subsequently associated with fewer residual ST changes at hospital discharge.

Originalsprog	Engelsk
Tidsskrift	Circulation
Vol/bind	125
Udgave nummer	3
Sider (fra-til)	514-21
Antal sider	8
ISSN	0009-7322
DOI	https://doi.org/10.1161/CIRCULATIONAHA.111.047530
Status	Udgivet - 2012

Adgang til dokumentet

10.1161/CIRCULATIONAHA.111.047530

Citationsformater

Armstrong, P. W., Siha, H., Fu, Y., Westerhout, C. M., Steg, P. G., James, S. K., Storey, R. F., Horrow, J., Katus, H., Clemmensen, P., Harrington, R. A., & Wallentin, L. (2012). ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy. Circulation, 125(3), 514-21. https://doi.org/10.1161/CIRCULATIONAHA.111.047530

Armstrong, PW, Siha, H, Fu, Y, Westerhout, CM, Steg, PG, James, SK, Storey, RF, Horrow, J, Katus, H, Clemmensen, P, Harrington, RA & Wallentin, L 2012, 'ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial: insights from the ECG substudy', Circulation, bind 125, nr. 3, s. 514-21. https://doi.org/10.1161/CIRCULATIONAHA.111.047530

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abstract = "Ticagrelor, when compared with clopidogrel, reduced the 12-month risk of vascular death/myocardial infarction and stroke in patients with ST-elevation acute coronary syndromes intended to undergo primary percutaneous coronary intervention in the PLATelet inhibition and patient Outcomes (PLATO) trial. This prespecified ECG substudy explored whether ticagrelor's association with vascular death and myocardial infarction within 1 year would be amplified by (1) the extent of baseline ST shift and (2) subsequently associated with fewer residual ST changes at hospital discharge.",

author = "Armstrong, {Paul W} and Hany Siha and Yuling Fu and Westerhout, {Cynthia M} and Steg, {Ph Gabriel} and James, {Stefan K} and Storey, {Robert F} and Jay Horrow and Hugo Katus and Peter Clemmensen and Harrington, {Robert A} and Lars Wallentin",

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doi = "10.1161/CIRCULATIONAHA.111.047530",

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T1 - ST-elevation acute coronary syndromes in the Platelet Inhibition and Patient Outcomes (PLATO) trial

T2 - insights from the ECG substudy

AU - Armstrong, Paul W

AU - Siha, Hany

AU - Fu, Yuling

AU - Westerhout, Cynthia M

AU - Steg, Ph Gabriel

AU - James, Stefan K

AU - Storey, Robert F

AU - Horrow, Jay

AU - Katus, Hugo

AU - Clemmensen, Peter

AU - Harrington, Robert A

AU - Wallentin, Lars

PY - 2012

Y1 - 2012

N2 - Ticagrelor, when compared with clopidogrel, reduced the 12-month risk of vascular death/myocardial infarction and stroke in patients with ST-elevation acute coronary syndromes intended to undergo primary percutaneous coronary intervention in the PLATelet inhibition and patient Outcomes (PLATO) trial. This prespecified ECG substudy explored whether ticagrelor's association with vascular death and myocardial infarction within 1 year would be amplified by (1) the extent of baseline ST shift and (2) subsequently associated with fewer residual ST changes at hospital discharge.

AB - Ticagrelor, when compared with clopidogrel, reduced the 12-month risk of vascular death/myocardial infarction and stroke in patients with ST-elevation acute coronary syndromes intended to undergo primary percutaneous coronary intervention in the PLATelet inhibition and patient Outcomes (PLATO) trial. This prespecified ECG substudy explored whether ticagrelor's association with vascular death and myocardial infarction within 1 year would be amplified by (1) the extent of baseline ST shift and (2) subsequently associated with fewer residual ST changes at hospital discharge.

U2 - 10.1161/CIRCULATIONAHA.111.047530

DO - 10.1161/CIRCULATIONAHA.111.047530

M3 - Journal article

C2 - 22179530

SN - 0009-7322

VL - 125

SP - 514

EP - 521

JO - Circulation

JF - Circulation

IS - 3

ER -