Suicide and mental illness in parents and risk of suicide in offspring : A birth cohort study

Holger Sørensen; Erik Lykke Mortensen; August Wang; Knud Juel; Leigh Silverton; Sarnoff Mednick

doi:10.1007/s00127-009-0495-5

Suicide and mental illness in parents and risk of suicide in offspring : A birth cohort study

Holger Sørensen, Erik Lykke Mortensen, August Wang, Knud Juel, Leigh Silverton, Sarnoff Mednick

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

44 Citationer (Scopus)

Abstract

Udgivelsesdato: 2009-Jan-23

Originalsprog	Engelsk
Tidsskrift	Social Psychiatry and Psychiatric Epidemiology
Vol/bind	44
Sider (fra-til)	748-51
ISSN	0933-7954
DOI	https://doi.org/10.1007/s00127-009-0495-5
Status	Udgivet - 2009

Adgang til dokumentet

10.1007/s00127-009-0495-5

Citationsformater

@article{6df41be04aa411de87b8000ea68e967b,

title = "Suicide and mental illness in parents and risk of suicide in offspring : A birth cohort study",

abstract = "BACKGROUND: A family history of completed suicide and psychiatric illness has been identified as risk factors for suicide. AIMS: To examine the risk of offspring suicide in relation to parental history of suicide and other parental risk factors. METHOD: The study population consisted of 7,177 adult offspring born 1959-1961 and their parents from the Copenhagen Perinatal Cohort. Cohort members and their parents who had committed suicide were identified in the Danish Causes of Death Registry (follow-up until December 31, 2005), while information on psychiatric hospitalisation history was obtained from the Danish Psychiatric Central Research Register. RESULTS: Forty-eight cohort members, 77 mothers and 133 fathers had committed suicide during the follow-up. Independent of parental psychiatric illness and social status, parental suicide significantly increased suicide risk in offspring (hazard ratio 4.40 with 95% CI 1.81-10.69). A stronger effect of parental suicide was observed in offspring without a history of psychiatric hospitalisation. CONCLUSION: Parental history of suicide is a risk factor for suicide in offspring, but primarily in offspring without psychiatric hospitalisation.",

author = "Holger S{\o}rensen and Mortensen, {Erik Lykke} and August Wang and Knud Juel and Leigh Silverton and Sarnoff Mednick",

year = "2009",

doi = "10.1007/s00127-009-0495-5",

language = "English",

volume = "44",

pages = "748--51",

journal = "Social Psychiatry and Psychiatric Epidemiology",

issn = "0933-7954",

publisher = "Springer Medizin",

}

TY - JOUR

T1 - Suicide and mental illness in parents and risk of suicide in offspring : A birth cohort study

AU - Sørensen, Holger

AU - Mortensen, Erik Lykke

AU - Wang, August

AU - Juel, Knud

AU - Silverton, Leigh

AU - Mednick, Sarnoff

PY - 2009

Y1 - 2009

N2 - BACKGROUND: A family history of completed suicide and psychiatric illness has been identified as risk factors for suicide. AIMS: To examine the risk of offspring suicide in relation to parental history of suicide and other parental risk factors. METHOD: The study population consisted of 7,177 adult offspring born 1959-1961 and their parents from the Copenhagen Perinatal Cohort. Cohort members and their parents who had committed suicide were identified in the Danish Causes of Death Registry (follow-up until December 31, 2005), while information on psychiatric hospitalisation history was obtained from the Danish Psychiatric Central Research Register. RESULTS: Forty-eight cohort members, 77 mothers and 133 fathers had committed suicide during the follow-up. Independent of parental psychiatric illness and social status, parental suicide significantly increased suicide risk in offspring (hazard ratio 4.40 with 95% CI 1.81-10.69). A stronger effect of parental suicide was observed in offspring without a history of psychiatric hospitalisation. CONCLUSION: Parental history of suicide is a risk factor for suicide in offspring, but primarily in offspring without psychiatric hospitalisation.

AB - BACKGROUND: A family history of completed suicide and psychiatric illness has been identified as risk factors for suicide. AIMS: To examine the risk of offspring suicide in relation to parental history of suicide and other parental risk factors. METHOD: The study population consisted of 7,177 adult offspring born 1959-1961 and their parents from the Copenhagen Perinatal Cohort. Cohort members and their parents who had committed suicide were identified in the Danish Causes of Death Registry (follow-up until December 31, 2005), while information on psychiatric hospitalisation history was obtained from the Danish Psychiatric Central Research Register. RESULTS: Forty-eight cohort members, 77 mothers and 133 fathers had committed suicide during the follow-up. Independent of parental psychiatric illness and social status, parental suicide significantly increased suicide risk in offspring (hazard ratio 4.40 with 95% CI 1.81-10.69). A stronger effect of parental suicide was observed in offspring without a history of psychiatric hospitalisation. CONCLUSION: Parental history of suicide is a risk factor for suicide in offspring, but primarily in offspring without psychiatric hospitalisation.

U2 - 10.1007/s00127-009-0495-5

DO - 10.1007/s00127-009-0495-5

M3 - Journal article

C2 - 19169611

SN - 0933-7954

VL - 44

SP - 748

EP - 751

JO - Social Psychiatry and Psychiatric Epidemiology

JF - Social Psychiatry and Psychiatric Epidemiology

ER -