Sulodexide for kidney protection in type 2 diabetes patients with microalbuminuria: a randomized controlled trial

Edmund J Lewis, Julia B Lewis, Tom Greene, Lawrence G Hunsicker, Tomas Berl, Marc A Pohl, Dick de Zeeuw, Hiddo Lambers Heerspink, Richard D Rohde, Robert C Atkins, Anne T Reutens, David K Packham, Itamar Raz, Collaborative Study Group, Birger Thorsteinsson

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    107 Citationer (Scopus)

    Abstract

    Sulodexide, a heterogenous group of sulfated glycosaminoglycans, includes low-molecular-weight heparin (~80% ± 8%), high-molecular-weight heparin (~5% ± 3%), and dermatan (~20% ± 8%), with a mean molecular weight of ~9 kDa. The drug is absorbed orally and has no anticoagulant effect in the doses used. Small preliminary studies consistently showed sulodexide to be associated with decreased albuminuria in patients with diabetes.
    OriginalsprogEngelsk
    TidsskriftAmerican Journal of Kidney Diseases
    Vol/bind58
    Udgave nummer5
    Sider (fra-til)729-36
    Antal sider8
    ISSN0272-6386
    DOI
    StatusUdgivet - 2011

    Bibliografisk note

    deltagelse i study group

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