Synchronized renal blood flow dynamics mapped with wavelet analysis of laser speckle flowmetry data

Alexey R Brazhe, Donald J Marsh, Niels-Henrik von Holstein-Rathlou, Olga Sosnovtseva

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

21 Citationer (Scopus)

Abstract

Full-field laser speckle microscopy provides real-time imaging of superficial blood flow rate. Here we apply continuous wavelet transform to time series of speckle-estimated blood flow from each pixel of the images to map synchronous patterns in instantaneous frequency and phase on the surface of rat kidneys. The regulatory mechanism in the renal microcirculation generates oscillations in arterial blood flow at several characteristic frequencies. Our approach to laser speckle image processing allows detection of frequency and phase entrainments, visualization of their patterns, and estimation of the extent of synchronization in renal cortex dynamics.

OriginalsprogEngelsk
Artikelnummere105879
TidsskriftPloS one
Vol/bind9
Udgave nummer9
Sider (fra-til)1-9
Antal sider9
ISSN1932-6203
DOI
StatusUdgivet - 2014

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