Synovial sarcoma mechanisms: a series of unfortunate events

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8 Citationer (Scopus)

Abstract

Human synovial sarcoma is caused by a chromosome translocation, which fuses DNA encoding SSX to that encoding the SS18 protein. Kadoch and Crabtree now show that the resulting cellular transformation stems from disruption of the normal architecture and function of the human SWI/SNF (BAF) complex.
OriginalsprogEngelsk
TidsskriftCell
Vol/bind153
Udgave nummer1
Sider (fra-til)11-2
Antal sider2
ISSN0092-8674
DOI
StatusUdgivet - 28 mar. 2013

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