Synthesis of substituted 2-cyanoarylboronic esters

Morten Lysén; Henriette M Hansen; Mikael Begtrup; Jesper L Kristensen

doi:10.1021/jo052400g

Synthesis of substituted 2-cyanoarylboronic esters

Morten Lysén, Henriette M Hansen, Mikael Begtrup, Jesper L Kristensen

LUKKET: Medicinal Chemistry Research

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

16 Citationer (Scopus)

Abstract

The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.

Originalsprog	Engelsk
Tidsskrift	Journal of Organic Chemistry
Vol/bind	71
Udgave nummer	6
Sider (fra-til)	2518-20
Antal sider	3
ISSN	0022-3263
DOI	https://doi.org/10.1021/jo052400g
Status	Udgivet - 17 mar. 2006

Adgang til dokumentet

10.1021/jo052400g

Citationsformater

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title = "Synthesis of substituted 2-cyanoarylboronic esters",

abstract = "The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.",

keywords = "Boronic Acids, Molecular Structure, Stereoisomerism",

author = "Morten Lys{\'e}n and Hansen, {Henriette M} and Mikael Begtrup and Kristensen, {Jesper L}",

year = "2006",

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doi = "10.1021/jo052400g",

language = "English",

volume = "71",

pages = "2518--20",

journal = "Journal of Organic Chemistry",

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publisher = "American Chemical Society",

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TY - JOUR

T1 - Synthesis of substituted 2-cyanoarylboronic esters

AU - Lysén, Morten

AU - Hansen, Henriette M

AU - Begtrup, Mikael

AU - Kristensen, Jesper L

PY - 2006/3/17

Y1 - 2006/3/17

N2 - The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.

AB - The synthesis of substituted 2-cyanoarylboronic esters is described via lithiation/in situ trapping of the corresponding methoxy-, trifluoromethyl-, fluoro-, chloro-, and bromobenzonitriles. The crude arylboronic esters were obtained in high yields and purities and with good regioselectivities.

KW - Boronic Acids

KW - Molecular Structure

KW - Stereoisomerism

U2 - 10.1021/jo052400g

DO - 10.1021/jo052400g

M3 - Journal article

C2 - 16526808

SN - 0022-3263

VL - 71

SP - 2518

EP - 2520

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 6

ER -