Abstract
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Journal of Rheumatology |
| Vol/bind | 36 |
| Udgave nummer | 8 |
| Sider (fra-til) | 1811-5 |
| Antal sider | 5 |
| ISSN | 0315-162X |
| DOI | |
| Status | Udgivet - 2009 |
Bibliografisk note
Keywords: Arthritis, Psoriatic; Cross-Sectional Studies; Edema; Female; Finger Joint; Finger Phalanges; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; SynovitisAdgang til dokumentet
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I: Journal of Rheumatology, Bind 36, Nr. 8, 2009, s. 1811-5.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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TY - JOUR
T1 - Testing an OMERACT MRI scoring system for peripheral psoriatic arthritis in cross-sectional and longitudinal settings
AU - McQueen, Fiona
AU - Lassere, Marissa
AU - Duer-Jensen, Anne
AU - Wiell, Charlotte
AU - Conaghan, Philip G
AU - Gandjbakhch, Frédérique
AU - Hermann, Kay-Geert A
AU - Bird, Paul
AU - Bøyesen, Pernille
AU - Peterfy, Charles
AU - Ejbjerg, Bo
AU - Haavardsholm, Espen A
AU - Coates, Laura
AU - Østergaard, Mikkel
N1 - Keywords: Arthritis, Psoriatic; Cross-Sectional Studies; Edema; Female; Finger Joint; Finger Phalanges; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Synovitis
PY - 2009
Y1 - 2009
N2 - OBJECTIVE: Magnetic resonance imaging (MRI) is increasingly used to measure articular inflammation and damage in patients with psoriatic arthritis (PsA). We evaluated the reliability of a new OMERACT PsA MRI scoring system, PsAMRIS, in PsA fingers. METHODS: In 2 separate studies, MRI scans were obtained from patients with clinical evidence of synovitis or dactylitis of the fingers. For the first cross-sectional study, images were obtained at one timepoint. For the second longitudinal study, images were obtained at 2 timepoints, 6 weeks apart. Scans were scored using PsAMRIS in an international multireader setting, for synovitis, tenosynovitis, periarticular inflammation, bone edema, bone erosions, and bone proliferation. RESULTS: Global status scores from both datasets revealed moderate to high reliability for scoring most features, although reliability was poor for periarticular inflammation in the cross-sectional study. Change scores that reflected inflammatory activity also exhibited moderate to good reliability in the longitudinal exercise, despite there being very little absolute change in MRI synovitis or tenosynovitis observed in this dataset. At the distal interphalangeal joints, reliability for change scores was acceptable only for synovitis and tenosynovitis. CONCLUSION: Further development and testing of the PsAMRIS is planned to improve its performance as a clinical and research tool to identify and measure pathology in peripheral joint PsA.
AB - OBJECTIVE: Magnetic resonance imaging (MRI) is increasingly used to measure articular inflammation and damage in patients with psoriatic arthritis (PsA). We evaluated the reliability of a new OMERACT PsA MRI scoring system, PsAMRIS, in PsA fingers. METHODS: In 2 separate studies, MRI scans were obtained from patients with clinical evidence of synovitis or dactylitis of the fingers. For the first cross-sectional study, images were obtained at one timepoint. For the second longitudinal study, images were obtained at 2 timepoints, 6 weeks apart. Scans were scored using PsAMRIS in an international multireader setting, for synovitis, tenosynovitis, periarticular inflammation, bone edema, bone erosions, and bone proliferation. RESULTS: Global status scores from both datasets revealed moderate to high reliability for scoring most features, although reliability was poor for periarticular inflammation in the cross-sectional study. Change scores that reflected inflammatory activity also exhibited moderate to good reliability in the longitudinal exercise, despite there being very little absolute change in MRI synovitis or tenosynovitis observed in this dataset. At the distal interphalangeal joints, reliability for change scores was acceptable only for synovitis and tenosynovitis. CONCLUSION: Further development and testing of the PsAMRIS is planned to improve its performance as a clinical and research tool to identify and measure pathology in peripheral joint PsA.
U2 - 10.3899/jrheum.090351
DO - 10.3899/jrheum.090351
M3 - Journal article
C2 - 19671818
SN - 0315-162X
VL - 36
SP - 1811
EP - 1815
JO - Journal of Rheumatology
JF - Journal of Rheumatology
IS - 8
ER -