The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

Børge G Nordestgaard; Tom M Palmer; Marianne Benn; Jeppe Zacho; Anne Tybjaerg-Hansen; George Davey Smith; Nicholas J Timpson

doi:10.1371/journal.pmed.1001212

The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach

Børge G Nordestgaard, Tom M Palmer, Marianne Benn, Jeppe Zacho, Anne Tybjaerg-Hansen, George Davey Smith, Nicholas J Timpson

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

243 Citationer (Scopus)

Abstract

Adiposity, assessed as elevated body mass index (BMI), is associated with increased risk of ischemic heart disease (IHD); however, whether this is causal is unknown. We tested the hypothesis that positive observational associations between BMI and IHD are causal.

Originalsprog	Engelsk
Tidsskrift	P L o S Medicine
Vol/bind	9
Udgave nummer	5
Sider (fra-til)	e1001212
ISSN	1549-1277
DOI	https://doi.org/10.1371/journal.pmed.1001212
Status	Udgivet - 2012

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Citationsformater

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abstract = "Adiposity, assessed as elevated body mass index (BMI), is associated with increased risk of ischemic heart disease (IHD); however, whether this is causal is unknown. We tested the hypothesis that positive observational associations between BMI and IHD are causal.",

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AU - Nordestgaard, Børge G

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AU - Zacho, Jeppe

AU - Tybjaerg-Hansen, Anne

AU - Davey Smith, George

AU - Timpson, Nicholas J

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DO - 10.1371/journal.pmed.1001212

M3 - Journal article

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