The effectiveness of a high output/short duration radiofrequency current application technique in segmental pulmonary vein isolation for atrial fibrillation

Brian Nilsson; Xu Chen; Steen Pehrson; Jesper Hastrup Svendsen

doi:10.1093/europace/eul100

The effectiveness of a high output/short duration radiofrequency current application technique in segmental pulmonary vein isolation for atrial fibrillation

Brian Nilsson, Xu Chen, Steen Pehrson, Jesper Hastrup Svendsen

Institut for Klinisk Medicin

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

73 Citationer (Scopus)

Abstract

Udgivelsesdato: 2006-Nov

Originalsprog	Engelsk
Tidsskrift	Europace
Vol/bind	8
Udgave nummer	11
Sider (fra-til)	962-5
Antal sider	3
ISSN	1099-5129
DOI	https://doi.org/10.1093/europace/eul100
Status	Udgivet - 2006

Bibliografisk note

Keywords: Atrial Fibrillation; Catheter Ablation; Female; Heart Conduction System; Humans; Male; Middle Aged; Prognosis; Pulmonary Veins; Treatment Outcome

Adgang til dokumentet

10.1093/europace/eul100

Citationsformater

@article{b4e9c170a30011df928f000ea68e967b,

title = "The effectiveness of a high output/short duration radiofrequency current application technique in segmental pulmonary vein isolation for atrial fibrillation",

abstract = "AIMS: Segmental pulmonary vein (PV) isolation by radiofrequency (RF) catheter ablation has become a curative therapy for atrial fibrillation (AF). However, the long procedure time limits the wide application of this procedure. The aim of the current study was to compare a novel ablation technique with a high power output and short application time vs. a conventional technique using a low power output and long application time. METHODS AND RESULTS: The study included 90 consecutive patients (age 53+/-10 years; 66 men). Segmental PV isolation was performed by irrigated RF catheter ablation in both groups. In the conventional group (Group 1, 45 patients), the power output was limited to 30 W with a target temperature of 50 degrees C and an RF preset duration of 120 s. In the novel group (Group 2, 45 patients), the maximum power output was preset to 45 W, with a target temperature of 55 degrees C and duration of 20 s. In Group 2, a significant reduction in the PV isolation time (127+/-57 vs. 94+/-33 min, P<0.02), mean fluoroscopy time (73+/-23 vs. 55+/-16 min, P<0.001), and radiation dose was observed. According to the application time and number, Group 2 showed a reduction in RF application time, but a higher number of RF applications were required for creation of complete PV isolation. During a mean follow-up of 15+/-7 months, a total of 74% of patients in Group 1 and 76% of patients in Group 2 demonstrated stable SR. CONCLUSION: Segmental PV isolation using a high power output and short application time is safe and effective in PV isolation in patients with AF. This technique can significantly reduce the procedure and fluoroscopy time compared with a low-power output technique.",

author = "Brian Nilsson and Xu Chen and Steen Pehrson and Svendsen, {Jesper Hastrup}",

note = "Keywords: Atrial Fibrillation; Catheter Ablation; Female; Heart Conduction System; Humans; Male; Middle Aged; Prognosis; Pulmonary Veins; Treatment Outcome",

year = "2006",

doi = "10.1093/europace/eul100",

language = "English",

volume = "8",

pages = "962--5",

journal = "Europace",

issn = "1099-5129",

publisher = "Oxford University Press",

number = "11",

}

TY - JOUR

T1 - The effectiveness of a high output/short duration radiofrequency current application technique in segmental pulmonary vein isolation for atrial fibrillation

AU - Nilsson, Brian

AU - Chen, Xu

AU - Pehrson, Steen

AU - Svendsen, Jesper Hastrup

N1 - Keywords: Atrial Fibrillation; Catheter Ablation; Female; Heart Conduction System; Humans; Male; Middle Aged; Prognosis; Pulmonary Veins; Treatment Outcome

PY - 2006

Y1 - 2006

N2 - AIMS: Segmental pulmonary vein (PV) isolation by radiofrequency (RF) catheter ablation has become a curative therapy for atrial fibrillation (AF). However, the long procedure time limits the wide application of this procedure. The aim of the current study was to compare a novel ablation technique with a high power output and short application time vs. a conventional technique using a low power output and long application time. METHODS AND RESULTS: The study included 90 consecutive patients (age 53+/-10 years; 66 men). Segmental PV isolation was performed by irrigated RF catheter ablation in both groups. In the conventional group (Group 1, 45 patients), the power output was limited to 30 W with a target temperature of 50 degrees C and an RF preset duration of 120 s. In the novel group (Group 2, 45 patients), the maximum power output was preset to 45 W, with a target temperature of 55 degrees C and duration of 20 s. In Group 2, a significant reduction in the PV isolation time (127+/-57 vs. 94+/-33 min, P<0.02), mean fluoroscopy time (73+/-23 vs. 55+/-16 min, P<0.001), and radiation dose was observed. According to the application time and number, Group 2 showed a reduction in RF application time, but a higher number of RF applications were required for creation of complete PV isolation. During a mean follow-up of 15+/-7 months, a total of 74% of patients in Group 1 and 76% of patients in Group 2 demonstrated stable SR. CONCLUSION: Segmental PV isolation using a high power output and short application time is safe and effective in PV isolation in patients with AF. This technique can significantly reduce the procedure and fluoroscopy time compared with a low-power output technique.

AB - AIMS: Segmental pulmonary vein (PV) isolation by radiofrequency (RF) catheter ablation has become a curative therapy for atrial fibrillation (AF). However, the long procedure time limits the wide application of this procedure. The aim of the current study was to compare a novel ablation technique with a high power output and short application time vs. a conventional technique using a low power output and long application time. METHODS AND RESULTS: The study included 90 consecutive patients (age 53+/-10 years; 66 men). Segmental PV isolation was performed by irrigated RF catheter ablation in both groups. In the conventional group (Group 1, 45 patients), the power output was limited to 30 W with a target temperature of 50 degrees C and an RF preset duration of 120 s. In the novel group (Group 2, 45 patients), the maximum power output was preset to 45 W, with a target temperature of 55 degrees C and duration of 20 s. In Group 2, a significant reduction in the PV isolation time (127+/-57 vs. 94+/-33 min, P<0.02), mean fluoroscopy time (73+/-23 vs. 55+/-16 min, P<0.001), and radiation dose was observed. According to the application time and number, Group 2 showed a reduction in RF application time, but a higher number of RF applications were required for creation of complete PV isolation. During a mean follow-up of 15+/-7 months, a total of 74% of patients in Group 1 and 76% of patients in Group 2 demonstrated stable SR. CONCLUSION: Segmental PV isolation using a high power output and short application time is safe and effective in PV isolation in patients with AF. This technique can significantly reduce the procedure and fluoroscopy time compared with a low-power output technique.

U2 - 10.1093/europace/eul100

DO - 10.1093/europace/eul100

M3 - Journal article

C2 - 17043070

VL - 8

SP - 962

EP - 965

JO - Europace

JF - Europace

SN - 1099-5129

IS - 11

ER -