TY - JOUR
T1 - The endolymphatic sac, a potential endocrine gland?
AU - Qvortrup, K
AU - Rostgaard, J
AU - Holstein-Rathlou, N H
AU - Bretlau, P
N1 - Keywords: Animals; Endocrine Glands; Endolymphatic Sac; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Natriuretic Agents; Rats; Rats, Wistar
PY - 1999
Y1 - 1999
N2 - A previous investigation indicated that the chief cells of the endolymphatic sac produce an endogenous inhibitor of sodium re-absorption in the kidneys, which has tentatively been named "saccin". In this study, the ultrastructure of the endolymphatic sac and in particular the chief cells is described, demonstrating that this organ fulfils the morphological criteria of a potential endocrine gland. Accordingly, the chief cells are shown to exhibit all the organelles and characteristics of cells that simultaneously synthesize, secrete, absorb and digest proteins.
AB - A previous investigation indicated that the chief cells of the endolymphatic sac produce an endogenous inhibitor of sodium re-absorption in the kidneys, which has tentatively been named "saccin". In this study, the ultrastructure of the endolymphatic sac and in particular the chief cells is described, demonstrating that this organ fulfils the morphological criteria of a potential endocrine gland. Accordingly, the chief cells are shown to exhibit all the organelles and characteristics of cells that simultaneously synthesize, secrete, absorb and digest proteins.
M3 - Journal article
C2 - 10320075
VL - 119
SP - 194
EP - 199
JO - Acta Oto-Laryngologica
JF - Acta Oto-Laryngologica
SN - 0001-6489
IS - 2
ER -