TY - JOUR
T1 - The future of integrated structural biology
AU - Schwalbe, Harald
AU - Audergon, Pauline
AU - Haley, Natalie
AU - Amaro, Claudia Alen
AU - Agirre, Jon
AU - Baldus, Marc
AU - Banci, Lucia
AU - Baumeister, Wolfgang
AU - Blackledge, Martin
AU - Carazo, Jose Maria
AU - Carugo, Kristina Djinovic
AU - Celie, Patrick
AU - Felli, Isabella
AU - Hart, Darren J.
AU - Hauß, Thomas
AU - Lehtiö, Lari
AU - Lindorff-Larsen, Kresten
AU - Márquez, José
AU - Matagne, André
AU - Pierattelli, Roberta
AU - Rosato, Antonio
AU - Sobott, Frank
AU - Sreeramulu, Sridhar
AU - Steyaert, Jan
AU - Sussman, Joel L.
AU - Trantirek, Lukas
AU - Weiss, Manfred S.
AU - Wilmanns, Matthias
N1 - Publisher Copyright:
Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.
PY - 2024
Y1 - 2024
N2 - Instruct-ERIC, "the European Research Infrastructure Consortium for Structural biology research," is a pan-European distributed research infrastructure making high-end technologies and methods in structural biology available to users. Here, we describe the current state-of-the-art of integrated structural biology and discuss potential future scientific developments as an impulse for the scientific community, many of which are located in Europe and are associated with Instruct. We reflect on where to focus scientific and technological initiatives within the distributed Instruct research infrastructure. This review does not intend to make recommendations on funding requirements or initiatives directly, neither at the national nor the European level. However, it addresses future challenges and opportunities for the field, and foresees the need for a stronger coordination within the European and international research field of integrated structural biology to be able to respond timely to thematic topics that are often prioritized by calls for funding addressing societal needs.
AB - Instruct-ERIC, "the European Research Infrastructure Consortium for Structural biology research," is a pan-European distributed research infrastructure making high-end technologies and methods in structural biology available to users. Here, we describe the current state-of-the-art of integrated structural biology and discuss potential future scientific developments as an impulse for the scientific community, many of which are located in Europe and are associated with Instruct. We reflect on where to focus scientific and technological initiatives within the distributed Instruct research infrastructure. This review does not intend to make recommendations on funding requirements or initiatives directly, neither at the national nor the European level. However, it addresses future challenges and opportunities for the field, and foresees the need for a stronger coordination within the European and international research field of integrated structural biology to be able to respond timely to thematic topics that are often prioritized by calls for funding addressing societal needs.
U2 - 10.1016/j.str.2024.08.014
DO - 10.1016/j.str.2024.08.014
M3 - Review
C2 - 39293444
AN - SCOPUS:85206018289
SN - 0969-2126
VL - 32
SP - 1563
EP - 1580
JO - Structure (London, England : 1993)
JF - Structure (London, England : 1993)
IS - 10
ER -