Abstract
The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (~3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Science |
Vol/bind | 345 |
Udgave nummer | 6200 |
Antal sider | 9 |
ISSN | 0036-8075 |
DOI | |
Status | Udgivet - 2014 |
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The genetic prehistory of the New World Arctic. / Raghavan, Maanasa; DeGiorgio, Michael; Albrechtsen, Anders; Moltke, Ida; Skoglund, Pontus; Korneliussen, Thorfinn Sand; Grønnow, Bjarne; Appelt, Martin; Gulløv, Hans Christian; Friesen, T Max; Fitzhugh, William; Malmström, Helena Susanne; Rasmussen, Simon; Olsen, Jesper; Melchior, Linea Cecilie; Fuller, Benjamin T; Fahrni, Simon M; Stafford jr., Thomas; Grimes, Vaughan; Renouf, M A Priscilla; Cybulski, Jerome; Lynnerup, Niels; Lahr, Marta Mirazon; Britton, Kate; Knecht, Rick; Arneborg, Jette; Metspalu, Mait; Cornejo, Omar E; Malaspinas, Anna Sapfo; Wang, Yong; Rasmussen, Morten; Raghavan, Vibha; Hansen, Thomas van Overeem; Khusnutdinova, Elza; Pierre, Tracey Lynn; Dneprovsky, Kirill; Andreasen, Claus; Lange, Hans; Hayes, M Geoffrey; Coltrain, Joan; Spitsyn, Victor A; Götherström, Anders; Orlando, Ludovic Antoine Alexandre; Kivisild, Toomas; Villems, Richard; Crawford, Michael H; Nielsen, Finn Cilius; Dissing, Jørgen; Heinemeier, Jan; Meldgaard, Morten; Bustamante, Carlos; O'Rourke, Dennis H; Jakobsson, Mattias; Gilbert, M Thomas P; Nielsen, Rasmus; Willerslev, Eske.
I: Science, Bind 345, Nr. 6200, 2014.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
}
TY - JOUR
T1 - The genetic prehistory of the New World Arctic
AU - Raghavan, Maanasa
AU - DeGiorgio, Michael
AU - Albrechtsen, Anders
AU - Moltke, Ida
AU - Skoglund, Pontus
AU - Korneliussen, Thorfinn Sand
AU - Grønnow, Bjarne
AU - Appelt, Martin
AU - Gulløv, Hans Christian
AU - Friesen, T Max
AU - Fitzhugh, William
AU - Malmström, Helena Susanne
AU - Rasmussen, Simon
AU - Olsen, Jesper
AU - Melchior, Linea Cecilie
AU - Fuller, Benjamin T
AU - Fahrni, Simon M
AU - Stafford jr., Thomas
AU - Grimes, Vaughan
AU - Renouf, M A Priscilla
AU - Cybulski, Jerome
AU - Lynnerup, Niels
AU - Lahr, Marta Mirazon
AU - Britton, Kate
AU - Knecht, Rick
AU - Arneborg, Jette
AU - Metspalu, Mait
AU - Cornejo, Omar E
AU - Malaspinas, Anna Sapfo
AU - Wang, Yong
AU - Rasmussen, Morten
AU - Raghavan, Vibha
AU - Hansen, Thomas van Overeem
AU - Khusnutdinova, Elza
AU - Pierre, Tracey Lynn
AU - Dneprovsky, Kirill
AU - Andreasen, Claus
AU - Lange, Hans
AU - Hayes, M Geoffrey
AU - Coltrain, Joan
AU - Spitsyn, Victor A
AU - Götherström, Anders
AU - Orlando, Ludovic Antoine Alexandre
AU - Kivisild, Toomas
AU - Villems, Richard
AU - Crawford, Michael H
AU - Nielsen, Finn Cilius
AU - Dissing, Jørgen
AU - Heinemeier, Jan
AU - Meldgaard, Morten
AU - Bustamante, Carlos
AU - O'Rourke, Dennis H
AU - Jakobsson, Mattias
AU - Gilbert, M Thomas P
AU - Nielsen, Rasmus
AU - Willerslev, Eske
N1 - Copyright © 2014, American Association for the Advancement of Science.
PY - 2014
Y1 - 2014
N2 - The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (~3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago.
AB - The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (~3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago.
KW - Alaska
KW - Arctic Regions
KW - Base Sequence
KW - Bone and Bones
KW - Canada
KW - DNA, Mitochondrial
KW - Genome, Human
KW - Greenland
KW - Hair
KW - History, Ancient
KW - Human Migration
KW - Humans
KW - Inuits
KW - Molecular Sequence Data
KW - Siberia
KW - Survivors
KW - Tooth
U2 - 10.1126/science.1255832
DO - 10.1126/science.1255832
M3 - Journal article
C2 - 25170159
VL - 345
JO - Science
JF - Science
SN - 0036-8075
IS - 6200
ER -