TY - JOUR
T1 - The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions’ (EQ-5D) Questionnaire and Residential Status in the Elderly
T2 - A Prospective, Observational, Multicenter Study
AU - Jentzsch, Thorsten
AU - Lewis, Stephen J.
AU - Oitment, Colby
AU - Rienmüller, Anna
AU - Martin, Allan R.
AU - Nielsen, Christopher J.
AU - Shear-Yashuv, Hananel
AU - de Kleuver, Marinus
AU - Qiu, Yong
AU - Matsuyama, Yukihiro
AU - Lenke, Lawrence G.
AU - Alanay, Ahmet
AU - Pellisé-Urquiza, Ferran
AU - Cheung, Kenneth M. C.
AU - Spruit, Maarten
AU - Polly, David W.
AU - Sembrano, Jonathan N.
AU - Shaffrey, Christopher I.
AU - Smith, Justin S.
AU - Kelly, Michael P.
AU - Dahl, Benny
AU - Berven, Sigurd H.
AU - AO Spine Knowledge Forum Deformity
N1 - Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was organized and funded by AO Spine through the AO Spine Knowledge Forum Deformity, a focused group of international spine deformity experts. AO Spine is a clinical division of the AO Foundation, which is an independent medically-guided not-for-profit organization. Study support was provided directly through the AO Spine Research Department and the AO Innovation Translation Center, Clinical Evidence.
Funding Information:
Comité Ético de Investigación Clínica del Hospital Universitari Vall d’Hebron; 38121226Z, University of Virginia Institutional Review Board for Health Sciences Research; 17323, The Committees on Health Research Ethics Benny Dahl is supported by a grant for The Alfred Benzon Foundation for the Capital Region of Denmark; H-2-2014-FSP18, Ethics Committee of Hamamatsu University School of Medicine; 25-253, 17-049, Ethics Committee of Hamamatsu University School of Medicine; 17-049, Institutional Review Board of The Hong Kong/Hospital Authority Hong Kong West Cluster; UW 14-109, Acıbadem Maslak Hospital, Turkey; 2013-567, 2016-16/18, 2017-6/20, Institutional Review Board, University of Minnesota; 1312M46667, Nanjing University Ethics Committee; 2013-079, Medical Ethics Committee, Slotervaartziekenhuis, The Netherlands; U/14.066/P1425, University Health Network Research Ethic Board, Toronto; 13-6942, Human Research Protection Program, Committee on Human Research, University of California, San Francisco; 13-12727, and The Washington University in St. Louis Institutional Review Board; 201312094.
Publisher Copyright:
© The Author(s) 2023.
PY - 2024
Y1 - 2024
N2 - Study Design: Multicenter, international prospective study. Objective: This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status. Methods: As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID. Results: The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from.53 (SD.21) and 55.6 (SD 23.0) pre-operatively to.64 (SD.18) and 65.8 (SD 18.7) at 10 weeks,.74 (SD.18) and 72.7 (SD 18.1) at 12 months, and.73 (SD.20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was.22 (95% CI.15-.29). Conclusions: The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was.22. Patients living at home pre-operatively can expect to be able to live at home 2 years postoperatively.
AB - Study Design: Multicenter, international prospective study. Objective: This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of EuroQol 5-dimensions (EQ-5D), EQ-VAS, and residential status. Methods: As an ancillary study of 219 patients ≥60 years with spinal deformity undergoing primary instrumented fusion surgery of ≥5 levels, this study focuses on EQ-5D (3-L) as the primary outcome and EQ-VAS and residential status as secondary outcomes. Data on EQ-5D were compared between pre-operatively and postoperatively at 10 weeks, 12 months, and 24 months. An anchor-based approach was used to calculate the MCID. Results: The EQ-5D index and EQ-VAS, respectively, improved significantly at each time point compared to pre-operatively (from.53 (SD.21) and 55.6 (SD 23.0) pre-operatively to.64 (SD.18) and 65.8 (SD 18.7) at 10 weeks,.74 (SD.18) and 72.7 (SD 18.1) at 12 months, and.73 (SD.20) and 70.4 (SD 20.4) at 24 months). 217 (99.1%) patients lived at home pre-operatively, while 186 (88.6%), 184 (98.4%), and 172 (100%) did so at 10 weeks, 12 months, and 24 months, respectively. Our calculated MCID for the EQ-5D index at 1 year was.22 (95% CI.15-.29). Conclusions: The EQ-5D index significantly increased at each time point over 24 months after ≥5 level spinal deformity surgery in elderly patients. The MCID of the EQ-5D-3 L was.22. Patients living at home pre-operatively can expect to be able to live at home 2 years postoperatively.
KW - adult
KW - health care
KW - minimal clinically important difference
KW - outcome assessment
KW - residence characteristics
KW - scoliosis
KW - surgery
U2 - 10.1177/21925682231162574
DO - 10.1177/21925682231162574
M3 - Journal article
C2 - 36943086
AN - SCOPUS:85151075634
VL - 14
SP - 1978
EP - 1989
JO - Global Spine Journal
JF - Global Spine Journal
SN - 2192-5682
IS - 7
ER -