TY - JOUR
T1 - The influence of pituitary and gonadal hormones on serum levels of pregnancy-associated murine protein-1
AU - Hau, J.
AU - Gidley-Baird, A. A.
AU - Teisner, B.
AU - Svendsen, P.
AU - Westergaard, J. G.
PY - 1983
Y1 - 1983
N2 - Hypophysectomy of female mice resulted in the disappearance of pregnancy-associated murine protein-1 (PAMP-1) from the circulation within a week. Maintenance of physiological levels of oestrogen, progesterone, testosterone, LH, FSH or prolactin was not sufficient to maintain a normal PAMP-1 level in the hypophysectomized animals. However, administration of oestrogen in large doses to adult male mice with undetectable levels of circulating PAMP-1 caused PAMP-1 to appear in the blood. Testosterone treatment of females inhibited the PAMP-1 synthesis.
AB - Hypophysectomy of female mice resulted in the disappearance of pregnancy-associated murine protein-1 (PAMP-1) from the circulation within a week. Maintenance of physiological levels of oestrogen, progesterone, testosterone, LH, FSH or prolactin was not sufficient to maintain a normal PAMP-1 level in the hypophysectomized animals. However, administration of oestrogen in large doses to adult male mice with undetectable levels of circulating PAMP-1 caused PAMP-1 to appear in the blood. Testosterone treatment of females inhibited the PAMP-1 synthesis.
UR - http://www.scopus.com/inward/record.url?scp=0020616188&partnerID=8YFLogxK
U2 - 10.1530/acta.0.1040023
DO - 10.1530/acta.0.1040023
M3 - Journal article
C2 - 6414206
AN - SCOPUS:0020616188
VL - 104
SP - 23
EP - 26
JO - European Journal of Endocrinology
JF - European Journal of Endocrinology
SN - 0804-4643
IS - 1
ER -