@article{604b19b9d4d0453abfcdc455c3de5ec0,
title = "The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin",
abstract = "Erlotinib, an epidermal-growth-factor receptor inhibitor, belongs to a new generation of targeted cancer therapeutics. Gastrointestinal side-effects are common and have been markedly aggravated when erlotinib is combined with cytostatics. We examined the effects of erlotinib alone and combined with the cytostatic, cisplatin, on the gastrointestinal tract and examined whether glucagon-like peptide-2 (GLP-2), an intestinal hormone with potent intestinotrophic properties, might counteract the possible damaging effects of the treatments.",
keywords = "Animals, Antineoplastic Agents, Atrophy, Body Weight, Cisplatin, Dose-Response Relationship, Drug, Drug Interactions, Female, Gastroenteritis, Gastrointestinal Tract, Glucagon-Like Peptide 2, Mice, Mice, Inbred Strains, Protein Kinase Inhibitors, Quinazolines",
author = "Rasmussen, {Andreas Ros{\'e}n} and Niels-Erik Viby and Hare, {Kristine Juul} and Bolette Hartmann and Lars Thim and Holst, {Jens Juul} and Poulsen, {Steen Seier}",
year = "2010",
month = oct,
day = "1",
doi = "10.1007/s10620-009-1104-x",
language = "English",
volume = "55",
pages = "2785--96",
journal = "Digestive Diseases and Sciences",
issn = "0163-2116",
publisher = "Springer",
number = "10",
}